Correlation plots showing pairwise comparisons across a shared set of 3 M CpG sites covered by 10 reads or more in each dataset.

<p>A). Heatmap of the Pearson’s correlation coefficients for comparisons across all the library types, sequencing softwares, and cell types used in the study ordered by hierarchical clustering. B) The corresponding root mean square error (RMSE) values for the library/software comparisons in the same order as plotted in panel A.