Tracking clathrin and dynamins in dual genome-edited Dyn1a-eGFP and Dyn2-mRuby2 A549 cells.
- Saipraveen Srinivasan (418047)
- Christoph J. Burckhardt (255331)
- Madhura Bhave (184581)
- Zhiming Chen (1313025)
- Ping-Hung Chen (645738)
- Xinxin Wang (134010)
- Gaudenz Danuser (149033)
- Sandra L. Schmid (278737)
Publication date
April 2018
DOIAbstract
<p>(A) Representative TIRF images and corresponding kymographs of dynamic behavior of overexpressed SNAP-CLCa, Dyn2-mRuby2<sup>end</sup>, and Dyn1a-eGFP<sup>end</sup> in dual genome-edited A549 cells. See <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.2005377#pbio.2005377.s008" target="_blank">S3 Movie</a>. (B) Examples of Dyn1 and Dyn2 dynamics at individual CCPs (i–iv) and (C) their corresponding quantitative traces. CLCa, clathrin light chain a; Dyn1, dynamin-1.</p
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