IgG4-related sclerosing disease located on the right maxilla: a case report and review of literature

IgG4-related sclerosing disease is an immunologic disease which involves multiple organs, and it was always misdiagnosed as inflammation or malignant tumor. The salivary and lacrimal glands are always related when it occurs in the maxillofacial region. The histopathology of the lesion is most important in the diagnosis of the IgG4-related sclerosing disease. To make a definite diagnosis, clinical manifestation and increasing of serum IgG4 are also needed. We received a patient who had a hard mass of the right maxilla and a swollen left lacrimal gland. After series examinations, we made a confirmed diagnosis of the patient as IgG4-related sclerosing disease. IgG4-related sclerosing disease was rarely been reported and occurred extremely rare in maxilla. This case report detailed the experience of us to make a definite diagnosis for the patient and discussed the pathogenesis, diagnosis and treatment methods of IgG4-related sclerosing disease by consulting the previous articles.National Natural Science Foundation of China [81572654]; Shenzhen Innovation Committee Fundamental Research [JCYJ20150403091443303, JCYJ20150403091443286]SCI(E)REVIEWhyyang192@hotmail.com55766-5771