Mechanistic studies of transcriptional regulation by non-CpG methylated DNA

DNA methylation on CpG sites is the most common epigenetic modification.Recently,methylation in a non-CpG context was also found to occur widely on genomic DNA.However,how non-CpG methylation influences DNA/protein interactions and regulates transcription has not been wellDNA methylation on CpG sites is the most common epigenetic modification.Recently,methylation in a non-CpG context was also found to occur widely on genomic DNA.However,how non-CpG methylation influences DNA/protein interactions and regulates transcription has not been well中国生物物理学会、中国科学院生物物理研究所