Mechanisms for the cell shape change during dorsal closure

Dorsal closure(DC),an important processes during Drosophila embryogenesis,is a model system for cell sheet morphogenesis and wound healing.This process consists of the contraction of the amnioserosa(AS) cells and subsequent fusion of the adjacent epidermis.Hence it induces individual cell shape change,which isDorsal closure(DC),an important processes during Drosophila embryogenesis,is a model system for cell sheet morphogenesis and wound healing.This process consists of the contraction of the amnioserosa(AS) cells and subsequent fusion of the adjacent epidermis.Hence it induces individual cell shape change,which is中国生物物理学会、中国科学院生物物理研究所