Traffic wave of chemotactic bacteria

Chemotaxis is one of the most fundamental behaviors for organisms to sense the environment and direct their motion toward attractants and away from repellents.And it is simply two-component signaling pathways but one of the best-studies and well-known sensory signal transduction systems in biology.Single bacteria chemotaxis motion is well understand in Escherichia coli {E.coli),but the interaction between bacteria is poorly studied in both physical and chemical ways.Thus,the description of bacteria the group chemotaxis behavior is still a problem.In the present work,we design a agarose integrated microfluidic chip which can provide a steady linear chemical diffusion field and flow-free environment to study E.coli RP437 group chemotaxis behavior under controlled influx density.Our microfluidic device consist ten observation channels and one main channel which continuously sustain the influx by pump of injection syringe.Our observation channel provide a long range gradient of chemo-attractant(N-methyl-D-asparti...Chemotaxis is one of the most fundamental behaviors for organisms to sense the environment and direct their motion toward attractants and away from repellents.And it is simply two-component signaling pathways but one of the best-studies and well-known sensory signal transduction systems in biology.Single bacteria chemotaxis motion is well understand in Escherichia coli {E.coli),but the interaction between bacteria is poorly studied in both physical and chemical ways.Thus,the description of bacteria the groDalian Maritime University (China)、Waterloo Institute for Nanotechnology (Canada)、Beijing International Center for Theoretical a