Pluripotent stem cells can be induced from somatic cells,providing an unlimited cell resource,with potential for studying disease and use in regenerative medicine.We demonstrated that pluripotent stem cells can be generated from mouse somatic cells using a combination of seven small-molecule compounds.The chemically induced pluripotent stem cells resemble embryonic stem cells in terms of their gene expressionPluripotent stem cells can be induced from somatic cells,providing an unlimited cell resource,with potential for studying disease and use in regenerative medicine.We demonstrated that pluripotent stem cells can be generated from mouse somatic cells using a combination of seven small-molecule compounds.The chemically induced pluripotent ...
BACKGROUND: Pluripotent stem cells have been derived from a variety of sources such as from the inne...
The ability of small molecules to maintain self-renewal and to inhibit differentiation of pluripoten...
Bona fide embryonic stem cell (ESC) lines from livestock species have been challenging to derive and...
Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient-specific stem ce...
Mammalian development was generally considered a naturally unidirectional and irreversible process. ...
The recent discovery that it is possible to directly reprogramme somatic cells to an embryonic stem ...
The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by th...
The general idea of regenerative medicine is to fix or replace tissues or organs with live and patie...
Pluripotent stem cells can differentiate into nearly all types of cells in the body. This unique pot...
Both human and mouse somatic cells were reported to be reprogrammed to pluripotent stem cells (iPS c...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Stem cells, including both pluripotent stem cells and multipotent somatic stem cells, hold great pot...
Direct reprogramming of somatic cells into a pluripotent state has attracted enor-mous interest in b...
Stem cells are offering a considerable range of prospects to the biomedical research including novel...
SummaryRecent breakthroughs in using viral transduction of a few genes for the reprogramming of both...
BACKGROUND: Pluripotent stem cells have been derived from a variety of sources such as from the inne...
The ability of small molecules to maintain self-renewal and to inhibit differentiation of pluripoten...
Bona fide embryonic stem cell (ESC) lines from livestock species have been challenging to derive and...
Induced pluripotent stem cells (iPSCs) could be employed in the creation of patient-specific stem ce...
Mammalian development was generally considered a naturally unidirectional and irreversible process. ...
The recent discovery that it is possible to directly reprogramme somatic cells to an embryonic stem ...
The discovery that somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) by th...
The general idea of regenerative medicine is to fix or replace tissues or organs with live and patie...
Pluripotent stem cells can differentiate into nearly all types of cells in the body. This unique pot...
Both human and mouse somatic cells were reported to be reprogrammed to pluripotent stem cells (iPS c...
Embryonic stem (ES) cells are derived from cells embedded in the inner cell mass of embryonic blasto...
Stem cells, including both pluripotent stem cells and multipotent somatic stem cells, hold great pot...
Direct reprogramming of somatic cells into a pluripotent state has attracted enor-mous interest in b...
Stem cells are offering a considerable range of prospects to the biomedical research including novel...
SummaryRecent breakthroughs in using viral transduction of a few genes for the reprogramming of both...
BACKGROUND: Pluripotent stem cells have been derived from a variety of sources such as from the inne...
The ability of small molecules to maintain self-renewal and to inhibit differentiation of pluripoten...
Bona fide embryonic stem cell (ESC) lines from livestock species have been challenging to derive and...