The interior and exterior problems have been extensively studied in the field of reconstruction of computed tomography (CT) images, which lead to important theoretical and practical results. In this study, we formulate a middle problem of CT image reconstruction, which is more challenging than either the interior or exterior problems. In the middle problem of CT image reconstruction, projection data are measured through and only through the middle dough-like region, so that each projection profile misses data not only internally but also on both sides. For an object with a radially symmetric exterior, we proved that the middle problem could be uniquely solved if the middle ring-shaped zone is piecewise constant or there is a known sub-regio...