Background: The aim of this study was to investigate the expression and the clinicopathologic significance of DNA methyltransferase 3B (DNMT3B), phosphatase and tensin homolog (PTEN) and human MutL homologs 1 (hMLH1) in endometrial carcinomas between Han and Uygur women in Xinjiang. Material/Methods: The expression of DNMT3B, PTEN, and hMLH1 in endometrial carcinomas were assessed by immunohistochemistry, followed by an analysis of their relationship to clinical-pathological features and prognosis. Results: There were a 61.7% (95/154) overexpression of DNMT3B, 50.0% (77/154) loss of PTEN expression and 18.2% (28/154) loss of hMLH1 expression. The expression of DNMT3B and PTEN in endometrial carcinomas was statistically significantly dif...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Introduction: Mutation in p53 and phosphatase and tensin homolog (PTEN) genes are reported to be pre...
Loss of PTEN (phosphatase and tensin homolog) expression and microsatellite instability are two of t...
Copyright © 2015 H. Gbelcova ́ et al. This is an open access article distributed under the Creative ...
Objective: To determine [1] expression levels of both DNA methyltransferases (DNMTs) and methyl-CpG-...
Objective: To determine [1] expression levels of both DNA methyltransferases (DNMTs) and methyl-CpG-...
PURPOSE: The relationship between endometrial carcinoma and cellular metabolism is unknown. In endom...
Phosphatase and tensin homolog (PTEN) is a protein that acts as a tumor suppressor by dephosphorylat...
Endometrial carcinoma (EC) is the most common gynecological cancer. However, there is currently no r...
To explore the relationships between the expressions of estrogen receptor (ER), progestin receptor (...
The aim of this study was to determine the clinicopathologic significance of miR-145 and miR-143 dow...
Aims: PTEN is a recently identified tumour suppressor inactivated in a wide variety of human cancer...
To investigate the clinicopathologic and prognostic implications of phosphoinositide 3 kinase (PI3K)...
To study the role of hTERT and c-myc,P53,ER,PR in endometrial carcinoma carcinogenesis.The expressio...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Introduction: Mutation in p53 and phosphatase and tensin homolog (PTEN) genes are reported to be pre...
Loss of PTEN (phosphatase and tensin homolog) expression and microsatellite instability are two of t...
Copyright © 2015 H. Gbelcova ́ et al. This is an open access article distributed under the Creative ...
Objective: To determine [1] expression levels of both DNA methyltransferases (DNMTs) and methyl-CpG-...
Objective: To determine [1] expression levels of both DNA methyltransferases (DNMTs) and methyl-CpG-...
PURPOSE: The relationship between endometrial carcinoma and cellular metabolism is unknown. In endom...
Phosphatase and tensin homolog (PTEN) is a protein that acts as a tumor suppressor by dephosphorylat...
Endometrial carcinoma (EC) is the most common gynecological cancer. However, there is currently no r...
To explore the relationships between the expressions of estrogen receptor (ER), progestin receptor (...
The aim of this study was to determine the clinicopathologic significance of miR-145 and miR-143 dow...
Aims: PTEN is a recently identified tumour suppressor inactivated in a wide variety of human cancer...
To investigate the clinicopathologic and prognostic implications of phosphoinositide 3 kinase (PI3K)...
To study the role of hTERT and c-myc,P53,ER,PR in endometrial carcinoma carcinogenesis.The expressio...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Carcinosarcomas (malignant mixed Mullerian tumors) of the uterus are rare and aggressive malignancie...
Introduction: Mutation in p53 and phosphatase and tensin homolog (PTEN) genes are reported to be pre...