Human serum amyloid P (hSAP), a member of the pentraxin family, inhibits the activation of fibrocytes in culture and inhibits experimental renal, lung, skin and cardiac fibrosis. As hepatic inflammation is one of the causes of liver fibrosis, in the present study, we investigated the hepatoprotective effects of hSAP against carbon tetrachloride (CCl4)-induced liver injury. Our data indicated that hSAP attenuated hepatic histopathological abnormalities and significantly decreased inflammatory cell infiltration and pro-inflammatory factor expression. Moreover, CCl4-induced apoptosis in the mouse liver was inhibited by hSAP, as measured by terminal-deoxynucleotidyl transferase mediated nick-end labeling (TUNEL) assay and cleaved caspase-3 expr...
Pentraxins such as serum amyloid P (SAP; also known as PTX2) regulate several aspects of the innate ...
Rong Wang*, Fuxing Song*, Shengnan Li, Bin Wu, Yanqiu Gu, Yongfang YuanDepartment of Pharmacy, Shang...
This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-induced ac...
Human serum amyloid P (hSAP), a member of the pentraxin family, inhibits the activation of...
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly ...
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly ...
The chemokine CCL5 is involved in the recruitment of immune cells and a subsequent activation of hep...
ObjectiveTo investigate the dynamic change of hepcidin in liver fibrosis induced by CCl4 among mice....
Topic: 2 Acute Liver FailureThis journal suppl. entitled: APASL Liver Week 2013BACKGROUND/AIMS: The ...
Procyanidin B2 has demonstrated several health benefits and medical properties. However, its protect...
Acute liver disease is characterized by inflammation, oxidative stress and necrosis, which can great...
Liver diseases represent a major health problem worldwide, in particular, acute liver injury is asso...
Background and Aim: To investigate whether double-knockdown of PHD1 and Keap1 in mice could enhance ...
The effects of carbon tetrachloride (CCl(4)) treatment on acute liver damage in knock out (heat shoc...
The purpose of this research was to evaluate whether maltol could protect from hepatic injury induce...
Pentraxins such as serum amyloid P (SAP; also known as PTX2) regulate several aspects of the innate ...
Rong Wang*, Fuxing Song*, Shengnan Li, Bin Wu, Yanqiu Gu, Yongfang YuanDepartment of Pharmacy, Shang...
This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-induced ac...
Human serum amyloid P (hSAP), a member of the pentraxin family, inhibits the activation of...
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly ...
Serum amyloid A (SAA) is an evolutionary highly conserved acute phase protein that is predominantly ...
The chemokine CCL5 is involved in the recruitment of immune cells and a subsequent activation of hep...
ObjectiveTo investigate the dynamic change of hepcidin in liver fibrosis induced by CCl4 among mice....
Topic: 2 Acute Liver FailureThis journal suppl. entitled: APASL Liver Week 2013BACKGROUND/AIMS: The ...
Procyanidin B2 has demonstrated several health benefits and medical properties. However, its protect...
Acute liver disease is characterized by inflammation, oxidative stress and necrosis, which can great...
Liver diseases represent a major health problem worldwide, in particular, acute liver injury is asso...
Background and Aim: To investigate whether double-knockdown of PHD1 and Keap1 in mice could enhance ...
The effects of carbon tetrachloride (CCl(4)) treatment on acute liver damage in knock out (heat shoc...
The purpose of this research was to evaluate whether maltol could protect from hepatic injury induce...
Pentraxins such as serum amyloid P (SAP; also known as PTX2) regulate several aspects of the innate ...
Rong Wang*, Fuxing Song*, Shengnan Li, Bin Wu, Yanqiu Gu, Yongfang YuanDepartment of Pharmacy, Shang...
This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-induced ac...