A Chemoselective N-Arylation Reaction of 2-Aminopyridine Derivatives with Arynes
- Cheng, Bin
- Wei, Jian
- Zu, Bing
- Zhao, Jianfei
- Wang, Taimin
- Duan, Xiaoguang
- Wang, Renqi
- Li, Yun
- Zhai, Hongbin
Publication date
January 2017
DOI Publisher
JOURNAL OF ORGANIC CHEMISTRY ISSN
0022-3263 Journal
0022-3263 Citation count (estimate)
2Abstract
A chemoselective N-arylation reaction of 2-aminopyridine derivatives with arynes in good to excellent yields has been described. The N-arylation products could be further applied to the facile construction of benzoisoquinuclidines and isoquinuclidines as well as pyrido[1,2-a]-benzimidazoles.NSFC [21472072, 21302077, 21290183]; Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT) [IRT_15R28]; FRFCU [lzujbky-2016-ct02, lzujbky-2014-188]; "111" Program of MOESCI(E)ARTICLE189410-94178
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