Improved cytocompatibility of Mg-1Ca alloy modified by Zn ion implantation and deposition

The Mg-1Ca alloy has been modified by Zn ion implantation and deposition (II&D) using metal vapor vacuum arc plasma source (MEVVA). The surface characteristics, corrosion behavior and cytocompatibility were investigated. The auger electron spectroscopy (AES) results showed that a uniform ZnO layer was formed on the surface of Mg-1Ca alloy. The electrochemical measurements revealed that the corrosion potential has been increased, and a comparable corrosion current density in the simulated body fluid (SBF) was obtained for the Zn-modified Mg-1Ca alloy. The indirect cell viability evaluation and direct cell culture results indicated that the cytocompatibility of MC3T3-E1 cells on the Mg-1Ca alloy was improved by the ZnO layer on the surface. (C) 2017 Elsevier B.V. All rights reserved.National Natural Science Foundation of China (NSFC) [51431002]SCI(E)ARTICLE87-8920