根据世界卫生组织的最新统计数据,全球癌症每年新发病例约1 400多万人,同时约有820万人因癌症死亡,其中90%是因肿瘤的复发转移导致.恶性肿瘤给患者造成的危害关键就在于它能够转移,因此肿瘤转移始终是肿瘤防治的重大课题及研究难点.如果能够精准了解并掌握肿瘤转移的规律和机制,控制转移发生、发展的关键环节,肿瘤问题就能够得到根本的解决.国家自然科学基金; 国家重点基础研究发展计划(973计划)(2010CB529402)资助Supported by the National Natural Science Foundation of China; the National Basic Research Program of China (973 Program)中国科学引文数据库(CSCD)2188-1954
The ATP-gated P2X7 has been shown to play an important role in invasiveness and metastasis of some t...
1 - ArticleIntroduction: The poor efficacy of various anti-cancer treatments against metastatic cell...
Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenos...
We previously found that in addition to anti-proliferation function, extracellular ATP had a pro-inv...
© 2019 The Author(s). Background: Extracellular ATP (eATP) was shown to induce epithelial-mesenchyma...
甲胎蛋白(alpha-fetoprotein,AFP)的功能一直是个谜.由于其在胎儿体内含量很高,过去国内外学者多认为AFP的主要生理功能是参与血液的物质运输和免疫调节.但是近期研究发现AFP能抑制细...
ATP 合成酶在所有生物體中皆存在,且通常位於真核細胞粒線體的內膜上。我們先前的研究發現,相較於正常細胞,ATP合成酶在乳癌組織中表現量較高,且在腫瘤細胞表面上出現 (Journal of Prote...
研究代表者研究分担者publisher研究種目:基盤研究(C); 研究期間:2009~2011; 課題番号:21580132;研究成果の概要(和文):Trichothecium roseumの生...
转移灶克隆形成的概念由Weinberg等人在2011年提出,是指肿瘤细胞从原发灶脱落,经转移到达潜在的位点,在重新获得增殖能力后,由微小转移灶逐步生长扩大,形成肉眼可见的转移灶的过程.该过程是转移中的...
Under nonpathological conditions, the extracellular nucleotide concentration remains constant and lo...
近年来,研究肿瘤微环境中各种细胞及分子对肿瘤转移的影响已经成为肿瘤研究领域的热点。本文在回顾了近年来此方面的主要进展的基础上,对主要细胞/分子影响肿瘤转移不同方面的机制及阐明不同成分之间及与肿瘤细胞之...
科学研究費補助金研究成果報告書研究種目: 基盤研究(C)研究期間: 2007~2008課題番号: 19590207研究代表者: 尾松 万里子(滋賀医科大学・医学部・准教授)マウスの前駆脂肪細胞である3...
Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenos...
Extracellular adenosine 5-triphosphate (ATP), secreted by living cancer cells or released by necroti...
Accumulating evidence indicates that the acidic microenvironments critically influence malignant beh...
The ATP-gated P2X7 has been shown to play an important role in invasiveness and metastasis of some t...
1 - ArticleIntroduction: The poor efficacy of various anti-cancer treatments against metastatic cell...
Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenos...
We previously found that in addition to anti-proliferation function, extracellular ATP had a pro-inv...
© 2019 The Author(s). Background: Extracellular ATP (eATP) was shown to induce epithelial-mesenchyma...
甲胎蛋白(alpha-fetoprotein,AFP)的功能一直是个谜.由于其在胎儿体内含量很高,过去国内外学者多认为AFP的主要生理功能是参与血液的物质运输和免疫调节.但是近期研究发现AFP能抑制细...
ATP 合成酶在所有生物體中皆存在,且通常位於真核細胞粒線體的內膜上。我們先前的研究發現,相較於正常細胞,ATP合成酶在乳癌組織中表現量較高,且在腫瘤細胞表面上出現 (Journal of Prote...
研究代表者研究分担者publisher研究種目:基盤研究(C); 研究期間:2009~2011; 課題番号:21580132;研究成果の概要(和文):Trichothecium roseumの生...
转移灶克隆形成的概念由Weinberg等人在2011年提出,是指肿瘤细胞从原发灶脱落,经转移到达潜在的位点,在重新获得增殖能力后,由微小转移灶逐步生长扩大,形成肉眼可见的转移灶的过程.该过程是转移中的...
Under nonpathological conditions, the extracellular nucleotide concentration remains constant and lo...
近年来,研究肿瘤微环境中各种细胞及分子对肿瘤转移的影响已经成为肿瘤研究领域的热点。本文在回顾了近年来此方面的主要进展的基础上,对主要细胞/分子影响肿瘤转移不同方面的机制及阐明不同成分之间及与肿瘤细胞之...
科学研究費補助金研究成果報告書研究種目: 基盤研究(C)研究期間: 2007~2008課題番号: 19590207研究代表者: 尾松 万里子(滋賀医科大学・医学部・准教授)マウスの前駆脂肪細胞である3...
Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenos...
Extracellular adenosine 5-triphosphate (ATP), secreted by living cancer cells or released by necroti...
Accumulating evidence indicates that the acidic microenvironments critically influence malignant beh...
The ATP-gated P2X7 has been shown to play an important role in invasiveness and metastasis of some t...
1 - ArticleIntroduction: The poor efficacy of various anti-cancer treatments against metastatic cell...
Tumor microenvironment of solid tumors is characterized by a strikingly high concentration of adenos...