Clinical value of early hypertonic saline liquid resuscitation on acute pancreatitis

目的 探讨对急性胰腺炎(AP)实施早期高渗盐水液体复苏的临床效果及价值.方法 选择2015年3月～2016年6月期间在本院接受治疗的90例AP患者随机分为对照组和观察组各45例,对照组给予林格氏波液体复苏,观察组给予高渗盐水液体复苏,观察两组患者临床复苏效果.结果 观察组总有效率为97.73％,显著高于对照组的75.00％ (P＜0.05);炎症反应相关指标、肠黏膜屏障功能改善程度均显著优于对照组(P＜0.05);观察组治疗后相关并发症的发生率均明显低于对照组,患者预后效果明显优于对照组,组间比较均有显著性差异(P＜0.05).结论 对急性胰腺炎患者实施早期高渗盐水液体复苏可取得更理想的治疗效果,可促进患者体内炎症反应、肠黏膜屏障功能得到更好改善,还能降低并发症发生率.Objective To discuss the clinical value of early hypertonic saline liquid resuscitation on acute pancreatitis.Methods 90 patients with AP were randomly divided into control group and observation group,which were treated with Ringer's solution resuscitation and hypertonic saline liquid resuscitation.The recovery effects were observed.Results The total effective rate of observation group (97.73 ％) was significantly higher than that of control group (75.00％,P＜0.05).The intestinal mucosal barrier function of observation group was significantly greater than that of the control group (P＜0.05).The incidence of related complications of observation group was significantly lower than that of the control group.The prognosis effect of observation group was better than that of control group (P＜0.05).Conclusion The early hypertonic saline liquid resuscitation for acute pancreatitis can obtain better treatment effect,promote the patient's body inflammatory reaction,improve intestinal mucous membrane barrier function and reduce the probability of complications.91264-12672