<正>It was ever thought that genomic information is transmitted faithfully from generation to generation.But our current knowledge does not indicate that it is the case.For example,genomic variations can be generated from DNA replication infidelity and unequal chromosome segregation.Natural decay of DNA molecules is also a fundamental source of changingSCI(E)PubMed3119-1211
Stability and function of eukaryotic genomes are closely linked to chromatin structure and organizat...
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stre...
Genome evolution is the process by which the content and organization of a species ' genetic in...
Many biologists assume that eukaryotic genomes are transmitted stably between generations with only ...
The genome in each of our normal cells acquires somatic genetic changes throughout life [1]. The bur...
Accurate and efficient replication of the human genome occurs in the context of an array of constitu...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
One of the fundamental challenges facing the cell is to accurately copy its geneticmaterial to daugh...
The conservation of genetic information through the ages can not be explained unless one assumes the...
Both theory and experimentation suggest that during development, the DNA of multicellular organisms,...
All living organisms need to duplicate their genetic information while protecting it from unwanted m...
The ability of a eukaryotic cell to precisely and accurately replicate its DNA is crucial to maintai...
Well-nourished cells in a favorable environment (well-supplied with growth factors, cytokines, and/o...
Aberrant changes to the genome structure underlie numerous human diseases such as cancers. The funct...
Stability and function of eukaryotic genomes are closely linked to chromatin structure and organizat...
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stre...
Genome evolution is the process by which the content and organization of a species ' genetic in...
Many biologists assume that eukaryotic genomes are transmitted stably between generations with only ...
The genome in each of our normal cells acquires somatic genetic changes throughout life [1]. The bur...
Accurate and efficient replication of the human genome occurs in the context of an array of constitu...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
Increased propensity of alterations in the genome during the life cycle of cells is called as genomi...
One of the fundamental challenges facing the cell is to accurately copy its geneticmaterial to daugh...
The conservation of genetic information through the ages can not be explained unless one assumes the...
Both theory and experimentation suggest that during development, the DNA of multicellular organisms,...
All living organisms need to duplicate their genetic information while protecting it from unwanted m...
The ability of a eukaryotic cell to precisely and accurately replicate its DNA is crucial to maintai...
Well-nourished cells in a favorable environment (well-supplied with growth factors, cytokines, and/o...
Aberrant changes to the genome structure underlie numerous human diseases such as cancers. The funct...
Stability and function of eukaryotic genomes are closely linked to chromatin structure and organizat...
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stre...
Genome evolution is the process by which the content and organization of a species ' genetic in...
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