TNF-α competition protein inhibitor design

TNF-α is a pleiotropic cytokine involved in inflammation.This protein exerts its normal functions in inflammation response by binding to its endogenous receptor (TNFR),TNFRⅠand TNFRⅡ.However,aberrant production of TNF-αis often involved in autoimmune disorders such as arthritis,the inhibitors of ...TNF-α is a pleiotropic cytokine involved in inflammation.This protein exerts its normal functions in inflammation response by binding to its endogenous receptor (TNFR),TNFRⅠand TNFRⅡ.However,aberrant production of TNF-αis often involved in autoimmune disorders such as arthritis,the inhibitors of ...中国生物化学与分子生物学学会蛋白质专业委员会（The Chinese Protein Society）