Chemical Modifications of Aminoglycoside Antibiotics Targeting RNA

The increased awareness of the central role of RNA has led to realization that RNA,as structural and functional information accumulation,is also drug target to small molecular therapy.Aminoglycosides are a group of well-known antibiotics,which function through binding to specific sites in prokary...The increased awareness of the central role of RNA has led to realization that RNA,as structural and functional information accumulation,is also drug target to small molecular therapy.Aminoglycosides are a group of well-known antibiotics,which function through binding to specific sites in prokary...中国化学会