Discovery of 15-Lipoxygenase activators

Human reticulocyte 15-lipoxygenase(15-LOX) is a 75 kDa fatty acid dioxygenases that con-tain 1 gram atom non-heme,nonsulfur -bound iron per mole enzyme.In humans,15-LOX acts upon arachidonic acid(AA) to create a number of important lipid mediators in-cluding lipoxins which possess numerous anti-i...中国生物化学与分子生物学会(The Chinese Society of Biochemistry and Molecular Biology)