Relationship between low bone density and arteriosclerosis in young and middle-aged males

目的：探讨中青年男性骨密度降低与动脉硬化之间的关系。方法回顾性分析2015年5月至2015年10月在北京大学首钢医院参加体检的男性体检者404名，所有体检者均行骨密度和动脉硬化检查，同时完善实验室检查、人体指标测量。结果该人群骨密度降低的发生率为38.61%；骨密度低下组的年龄为47.62±7.84岁，骨密度正常组的年龄为45.44±7.00岁，差异具有统计学意义（ P ﹤0.05）；骨密度低下组的甘油三酯（ TG）水平（2.39±1.87 mmol/L）明显高于骨密度正常组（1.94±1.07 mmol/L），差异具有统计学意义（ P ﹤0.05）；骨密度低下组动脉硬化的发生率（32.05%）明显高于骨密度正常组（21.77%），差异具有统计学意义（ P ﹤0.05）。结论在中青年男性人群中，骨密度降低的发生率比较高；年龄增加、血脂水平的异常都有可能是该人群骨密度降低的危险因素；骨密度降低与动脉硬化之间在中青年男性人群中存在相互联系。Objective To study the relationship between low bone density and arteriosclerosis in young and middle-aged males. Meth-ods This research retrospectively analyzed 404 healthy men from May 2015 to October 2015 in Peking University Shougang hospital. All people were undertaken by bone mineral density( BMD)and arteriosclerosis examination. At the same time,their anthropometric indices,laboratory indi-ces were also obtained. Results The incidence of low bone density in all of people is 38. 61%. People in the low BMD group were at an age of (47. 62 ± 7. 84)years,which were significantly elder than those(45. 44 ± 7. 00 years)in normal BMD group( P ﹤0. 05). Serum content of TG was significantly higher in low BMD group(2. 39 ± 1. 87 mmol/L)than normal BMD group(1. 94 ± 1. 07 mmol/L)( P ﹤0. 05). The incidence of arteriosclerosis(32. 05%)was significantly higher than the normal BMD group(21. 77%)(P ﹤0. 05). Conclusion There is a high inci-dence of low bone density in young and middle-aged males. Aging and dyslipidemia may be risk factors of low bone density in young and middle-aged people. The declination of bone mineral density may be correlated with the occurrence of arteriosclerosis.中国科技核心期刊(ISTIC)9881-8831