One case analysis of antibacterials interaction with Warfarin

目的:通过临床药师参与1例感染性心内膜炎抗感染治疗期间华法林剂量调整的药学实践,探讨其在临床治疗中发挥的作用.方法:临床药师依靠药学知识尤其是药动学优势,抗菌药物治疗期间与医师一起共同参与药物治疗监测及制定华法林给药剂量方案.结果:经过反复调整华法林剂量,最终达到满意抗凝目标值.结论:临床药师参与临床治疗实践,有利于提高药物治疗水平.Objective:To explore the role of clinical pharmacists in clinical treatment by adjusting the dose of warfarin during the period of anti-infective treatment in a patient with infective endocarditis.Methods: The clinical pharmacists collaborated with clinicians monitored drug therapy and adjusted the dose of warfarin during the period of anti-infective treatment utilizing their pharmaceutical knowledge, especially pharmacokinetic knowledge.Results:After repeatedly adjusted the dose of warfrin, and eventually reached a satisfactory target value of anticoagulation.Conclusion: Clinical pharmacists involvement in clinical practice is helpful for improving the level of drug treatment.中国科技核心期刊(ISTIC)485-871