Speedup inverse treatment planning based on multi-core parallel simulated annealing

In order to realize the real time image-guided 4D prompt conformal intensity modulated radiotherapy in clinical practice using inverse optimization algorithm, the authors tested the global optimization search of the simulated annealing algorithm with a HP desk workstation and OpenMP multi thread library, which was further used for the optimization process for a virtual phantom and 4 real treatment plans of cancer patients. The results show that the method used in the test can speed up the search efficiency notably, if more CPU or core are chosen, the multi-core based parallel calculating technology can satisfy most requirements for 4D medical imaging in clinical at current time.EI06853-8584