Detection of deception with P300

Because event-related potentials (ERPs) could reflect dynamic changes in brain function during cognitive processes in human subjects, and the changes are independent of the activities of autonomic nervous system, they have been used as indicators of lie detection. Twenty subjects imagined they had committed burglary of an apartment. Guilty knowledge test (GKT) taking question-answers format was constructed according to the crime. For each of 18 questions, the corresponding five answers consisting of one relevant item (RI) and four irrelevant items (II) were presented serially after its presentation. S ignificant differences in P300 amplitude were found between RIs and IIs at F3, Fz and F4, but not at N400. We also compared the differences in P300 amplitude between RI and II among F3, Fz and F4. Only the difference between F3 and F4 reached significant level. These results suggested that we could utilize the P300 amplitude to distinguish guilt from innocence. Meanwhile, in the Views of actual applications, if the visual stimuli eliciting P300 component were semantic to right-handed subjects, F3 was a better location to record ERPs for detecting deception than F4, Fz.Clinical NeurologyNeurosciencesPhysiologyPsychiatryCPCI-S(ISTP)