Add to ORKGAIM: To explore the expression of cadherin isoforms in cultured human gastric carcinoma cells and its regulation. METHODS: The expressions of cell adhesion molecules (including E-cadherin, N-cadherin, a-catenin, P-catenin) and cadherin transcription factors including snail, slug and twist were determined by reverse transcriptase-polymerase chain reaction(RT-PCR), immunoblotting and immunofluorescence in SV40-immortalized human gastric cell line Ges-1 and human gastric cancer cell lines MGC-803, BGC-823 and SGC-7901. RESULTS: All cell lines expressed N-cadherin, but not E-cadherin. N-cadherin immunofluorescence was detected at cell membranous adherents junctions where co-localization with immunofluorescent staining of inner surface adh...
Detachment of cell-cell adhesion is indispensable for the first step of invasion and metastasis of c...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...
To explore cell malignant phenotype correlated changes of cell surface adhesion molecules and cell-c...
BACKGROUND: The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and...
Perturbation in E-cadherin expression leads to loss of cellular adhesion with possible consequence o...
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germlin...
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germlin...
To access full text version of this article. Please click on the hyperlink "View/Open" at the bottom...
Cadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cad...
Gastric cancer is the fifth most common cancer and the third most common cause of cancer death all o...
Aims E-cadherin, the main epithelial intercellular adhesion molecule, is abnormally expressed in man...
Dysfunction of E-cadherin and eaten in has been linked to invasiveness and differentiation of tumors...
Background and Aims: Cadherins and their associated molecules, such as α- catenin, have been shown r...
Background and Aims: Cadherins and their associated molecules, such as α- catenin, have been shown r...
Detachment of cell-cell adhesion is indispensable for the first step of invasion and metastasis of c...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...
To explore cell malignant phenotype correlated changes of cell surface adhesion molecules and cell-c...
BACKGROUND: The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and...
Perturbation in E-cadherin expression leads to loss of cellular adhesion with possible consequence o...
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germlin...
Hereditary diffuse gastric cancer (HDGC) is a dominantly inherited cancer syndrome caused by germlin...
To access full text version of this article. Please click on the hyperlink "View/Open" at the bottom...
Cadherin is an adhesion molecule and a superfamily of calcium-mediated membrane glycoproteins. E-cad...
Gastric cancer is the fifth most common cancer and the third most common cause of cancer death all o...
Aims E-cadherin, the main epithelial intercellular adhesion molecule, is abnormally expressed in man...
Dysfunction of E-cadherin and eaten in has been linked to invasiveness and differentiation of tumors...
Background and Aims: Cadherins and their associated molecules, such as α- catenin, have been shown r...
Background and Aims: Cadherins and their associated molecules, such as α- catenin, have been shown r...
Detachment of cell-cell adhesion is indispensable for the first step of invasion and metastasis of c...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...
Disruption of E-cadherin (CDH1 gene) expression, subcellular localization or function arises during ...