The locus coeruleus (LC) harbors a compact group of noradrenergic cell bodies projecting to virtually all parts of the central nervous system. By using combined measurements of amperometry and patch-clamp, quantal vesicle release of noradrenaline (NA) was detected as amperometric spikes, after depolarization of the LC neurons. After a pulse depolarization, the average latency of amperometric spikes was 1,870 ms, whereas the latency of glutamate-mediated excitatory postsynaptic currents was 1.6 ms. A substantial fraction of the depolarization-induced amperometric spikes originated from the somata. In contrast to glutamate-mediated excitatory postsynaptic currents, NA secretion was strongly modulated by the action potential frequency (0.5-50 ...
The locus coeruleus (LC) contains the majority of central noradrenergic neurons sending wide project...
The brain stem nucleus Locus Coeruleus (LC) is thought to modulate cortical excitability by norepine...
Cognitive theories assume that the locus coeruleus (LC), a brain stem neuromodulatory nucleus, broad...
Norepinephrine(NE) released from the nerve terminal of locus coeruleus (LC) neurons contribute to ab...
The Locus coeruleus (LC) modulates various neuronal circuits throughout the brain. Its unique archit...
Understanding forebrain neuromodulation by the noradrenergic locus coeruleus (LC) is fundamental for...
Noradrenergic neurons in the locus coeruleus (LC) release noradrenaline (NA) that acts via volume tr...
The Locus Coeruleus (LC) is a major source of noradrenaline (NE) for the cerebral cortex. Tonic stim...
Norepinephrine(NE)released from the nerve terminal of locus coeruleus(LC)neurons contributes to abou...
The locus coeruleus (LC) and ventral tegmental area (VTA) are the source of noradrenergic and dopami...
Background: Previous studies by our group suggest that extracellular dopamine (DA) and noradrenaline...
Whole-cell recordings were performed as described previously by the Jiang lab. Briefly, patch pipett...
The locus coeruleus(LC)contains the major group of noradrenergic cell bodies projecting to virtually...
Neuronal responses to sensory stimuli are not only driven by feedforward sensory pathways but also d...
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulate...
The locus coeruleus (LC) contains the majority of central noradrenergic neurons sending wide project...
The brain stem nucleus Locus Coeruleus (LC) is thought to modulate cortical excitability by norepine...
Cognitive theories assume that the locus coeruleus (LC), a brain stem neuromodulatory nucleus, broad...
Norepinephrine(NE) released from the nerve terminal of locus coeruleus (LC) neurons contribute to ab...
The Locus coeruleus (LC) modulates various neuronal circuits throughout the brain. Its unique archit...
Understanding forebrain neuromodulation by the noradrenergic locus coeruleus (LC) is fundamental for...
Noradrenergic neurons in the locus coeruleus (LC) release noradrenaline (NA) that acts via volume tr...
The Locus Coeruleus (LC) is a major source of noradrenaline (NE) for the cerebral cortex. Tonic stim...
Norepinephrine(NE)released from the nerve terminal of locus coeruleus(LC)neurons contributes to abou...
The locus coeruleus (LC) and ventral tegmental area (VTA) are the source of noradrenergic and dopami...
Background: Previous studies by our group suggest that extracellular dopamine (DA) and noradrenaline...
Whole-cell recordings were performed as described previously by the Jiang lab. Briefly, patch pipett...
The locus coeruleus(LC)contains the major group of noradrenergic cell bodies projecting to virtually...
Neuronal responses to sensory stimuli are not only driven by feedforward sensory pathways but also d...
The locus coeruleus (LC) houses the vast majority of noradrenergic neurons in the brain and regulate...
The locus coeruleus (LC) contains the majority of central noradrenergic neurons sending wide project...
The brain stem nucleus Locus Coeruleus (LC) is thought to modulate cortical excitability by norepine...
Cognitive theories assume that the locus coeruleus (LC), a brain stem neuromodulatory nucleus, broad...