Spontaneous chiral resolution directed by symmetry restriction and pi-pi interaction

In order to understand and rationally construct homochiral self-assembled structures from racemic molecules, two novel crystalline metal-organic frameworks with chiral cavities were developed. The homochirality of the layers in both MOFs was achieved by forming strong coordinate bonds between the C-3-symmetric cyclotriveratrylene and Zn4O(CO2)(6) cluster. By changing weak p-p interactions between organic building blocks, the achiral assembly of ZnCTV-1 was successfully transformed into a chiral assembly in ZnCTV-2. This study demonstrated a possible route for designing the synthesis of chiral MOF through weak interactions.Multidisciplinary SciencesSCI(E)0ARTICLEnull