Convenient syntheses of 2-alkyl(aryl)-4,5-diphenyloxazoles and 2-alkyl(aryl)-4-phenyloxazoles
- Pei, WW
- Li, SH
- Nie, XP
- Li, YW
- Pei, J
- Chen, BZ
- Wu, J
- Ye, XL
Publication date
January 1998
DOI Publisher
synthesis stuttgart ISSN
0039-7881 Journal
issn:0039-7881 Citation count (estimate)
23Abstract
The synthetic methods to prepare 2-alkyl(aryl)-4,5-diphenyloxazoles and 2-alkyl(aryl)-4-phenyloxazoles were improved on the basis of a mechanistic study of oxazole formation from alpha-hydroxy ketones (carboxylic esters of benzoin and phenacyl alcohols). By these methods, seven trisubstituted oxazoles and twelve disubstituted oxazoles of the title compounds were prepared.Chemistry, OrganicSCI(E)31ARTICLE91298-130
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