Add to ORKGBasic region-leucine zipper (bZIP) family of DNA-binding protein GCN4 truncate AC-[L-250] GCN4 (226-252)-GGC-OH and its two designed analogues were synthesized by solid phase method using Fmoc-strategy. Circular dichroism spectroscopy measurements showed that the DNA-binding affinity with target AP-1 site was reduced when Thr-236 in GCN4 basic region was replaced by valine or glutamine.Biochemistry & Molecular BiologySCI(E)0ARTICLE4245-252
ABSTRACT: Synthetic photocontrolled proteins could be powerful tools for probing cellular chemistry....
We aim to design novel proteins that link specific biochemical binding events, such as DNA recogniti...
酵母转录激活因子GCN4调控细胞中氨基酸的生物合成,是典型的含bZIP结构域的DNA结合蛋白.本文合成了天然蛋白GCN4的碱性区(226-252),并在其N末端引入色氨酸残基W,做为单体肽GCN4-W...
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAM...
The General Control Non-depressible protein 4 (GCN4) is a transcription factor found in Saccharomyce...
Several GCN4 bZIP TF models have previously been designed and synthesized. However, the synthetic ro...
'To whom correspondence should be addressed We report the complete structure determination of a...
The solution structure of an active synthetic peptide containing both the leucine zipper and the adj...
Dimerization is widely believed to be a requirement for the yeast transcriptional activator GCN4 to ...
We report the complete structure determination of a 34 residue synthetic peptide with the amino acid...
Yeast transcriptional activator GCN4(226-252)-GGC-NH2 and the designed Ac-[Q(236), Q(242)]GCN4(226-2...
The basic DNA recognition region of the GCN4 protein comprising 23 amino acids has been modified to ...
GCN4 is a transcriptional activator, found in S. Cerevisiae, that belongs to the well characterised ...
Affinity cleaving proteins have been synthesized based on the DNA-binding domain of the yeast trans...
The bZip proteins GCN4 and C/EBP differ in their DNA binding specificities: GCN4 binds well to the p...
ABSTRACT: Synthetic photocontrolled proteins could be powerful tools for probing cellular chemistry....
We aim to design novel proteins that link specific biochemical binding events, such as DNA recogniti...
酵母转录激活因子GCN4调控细胞中氨基酸的生物合成,是典型的含bZIP结构域的DNA结合蛋白.本文合成了天然蛋白GCN4的碱性区(226-252),并在其N末端引入色氨酸残基W,做为单体肽GCN4-W...
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAM...
The General Control Non-depressible protein 4 (GCN4) is a transcription factor found in Saccharomyce...
Several GCN4 bZIP TF models have previously been designed and synthesized. However, the synthetic ro...
'To whom correspondence should be addressed We report the complete structure determination of a...
The solution structure of an active synthetic peptide containing both the leucine zipper and the adj...
Dimerization is widely believed to be a requirement for the yeast transcriptional activator GCN4 to ...
We report the complete structure determination of a 34 residue synthetic peptide with the amino acid...
Yeast transcriptional activator GCN4(226-252)-GGC-NH2 and the designed Ac-[Q(236), Q(242)]GCN4(226-2...
The basic DNA recognition region of the GCN4 protein comprising 23 amino acids has been modified to ...
GCN4 is a transcriptional activator, found in S. Cerevisiae, that belongs to the well characterised ...
Affinity cleaving proteins have been synthesized based on the DNA-binding domain of the yeast trans...
The bZip proteins GCN4 and C/EBP differ in their DNA binding specificities: GCN4 binds well to the p...
ABSTRACT: Synthetic photocontrolled proteins could be powerful tools for probing cellular chemistry....
We aim to design novel proteins that link specific biochemical binding events, such as DNA recogniti...
酵母转录激活因子GCN4调控细胞中氨基酸的生物合成,是典型的含bZIP结构域的DNA结合蛋白.本文合成了天然蛋白GCN4的碱性区(226-252),并在其N末端引入色氨酸残基W,做为单体肽GCN4-W...