Topics
ethanolChemical substance
5, 6, 7, 8Work
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BeijingPlace
Peking UniversityAgent
acidChemical compound
HMG-CoAChemical substance
Xuezhikang capsule (ethanol extract of red yeast rice) which produced by Beijing WBL Peking University Biotech Co., Ltd., is a traditional Chinese medication with 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibiting activity. Clinical trials indicated that Xuezhikang with lipid-lowering action could reduce the risk of cardiac events and total mortality of Chinese coronary heart disease patients. To exactly explain the clinical features of Xuezhikang, we undertook a complete study of the chemical constituents of Xuezhikang. This study resulted in the isolation of a new monacolin analogue, named alpha, beta-dehydromonacolin L (1), along with two known compounds: monacolin L (2) and 3-(2, 6-dimethyl-1, 2, 4a, 5, 6, 7, 8, 8a-oct...
Red fermented rice, also known as red yeast rice, Hongqu, Anka or red Koji, is the fermented product...
One unusual aromatic monacolin analog, aromonacolin A (1), was isolated from the ethanolic extract o...
AbstractOne of the major causes of death is coronary heart disease which is usually caused by hyperc...
Statins inhibit the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), which is t...
Purpose. Nonalcoholic fatty liver disease (NAFLD) is a progressive and intractable disease associate...
Hypercholesterolemia is a risk factor to atherosclerosis and coronary heart disease II. The abnormal...
<p>Four new monacolin analogs, monacolin T (<b>1</b>), monacolin U (<b>2</b>) 6<i>a</i>-<i>O</i>-met...
supplement industries have proceeded without delay to produce a number of RYR formulations. These fo...
Two new dehydromonacolins (<b>1</b> and <b>3</b>), together with nine known monacolins (<b>4</b>–<b>...
Shih-Hung Lin,1 Kao-Jean Huang,1,2 Ching-Feng Weng,1 David Shiuan1 1Department of Life Science and ...
Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for...
Monacolins, as natural statins, form a class of fungal secondary metabolites and act as the specific...
Xuezhikang, extract of red yeast rice, is a traditional Chinese medicine with multiple cardioprotect...
Monacolins, as natural statins, form a class of fungal secondary metabolites and act as the specific...
The research aims to investigate the potential of natural products as inhibitors of HMG-CoA reductas...
Red fermented rice, also known as red yeast rice, Hongqu, Anka or red Koji, is the fermented product...
One unusual aromatic monacolin analog, aromonacolin A (1), was isolated from the ethanolic extract o...
AbstractOne of the major causes of death is coronary heart disease which is usually caused by hyperc...
Statins inhibit the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA reductase), which is t...
Purpose. Nonalcoholic fatty liver disease (NAFLD) is a progressive and intractable disease associate...
Hypercholesterolemia is a risk factor to atherosclerosis and coronary heart disease II. The abnormal...
<p>Four new monacolin analogs, monacolin T (<b>1</b>), monacolin U (<b>2</b>) 6<i>a</i>-<i>O</i>-met...
supplement industries have proceeded without delay to produce a number of RYR formulations. These fo...
Two new dehydromonacolins (<b>1</b> and <b>3</b>), together with nine known monacolins (<b>4</b>–<b>...
Shih-Hung Lin,1 Kao-Jean Huang,1,2 Ching-Feng Weng,1 David Shiuan1 1Department of Life Science and ...
Red yeast rice (RYR), produced by the fermentation of the Monascus purpureus mold, has been used for...
Monacolins, as natural statins, form a class of fungal secondary metabolites and act as the specific...
Xuezhikang, extract of red yeast rice, is a traditional Chinese medicine with multiple cardioprotect...
Monacolins, as natural statins, form a class of fungal secondary metabolites and act as the specific...
The research aims to investigate the potential of natural products as inhibitors of HMG-CoA reductas...
Red fermented rice, also known as red yeast rice, Hongqu, Anka or red Koji, is the fermented product...
One unusual aromatic monacolin analog, aromonacolin A (1), was isolated from the ethanolic extract o...
AbstractOne of the major causes of death is coronary heart disease which is usually caused by hyperc...
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