Background: Growth differentiation factor-9 (GDF9), a member of the bone morphogenetic protein (BMP) family and the transforming growth factor (TGF)-beta superfamily, has recently been implicated in the biological control of cancer cell behaviour. It has also been implicated in the development and spread of solid cancer. However, the role of GDF9 in kidney cancer remains to be investigated. In the present study, the expression of GDF9 in normal and malignant human kidney tissues and its molecular and cellular impact on human kidney cancer cells were investigated. Materials and Methods: The expression of GDF9 in human kidney tissues and kidney cancer cell lines (UMRC-2 and CAKI-2) was assessed at both the mRNA and protein levels using revers...
OBJECTIVE: To analyze the role of the transforming growth factor (TGF)-beta pathway in renal tumor...
Bone morphogenetic protein 9 (BMP9), a member of TGF-β superfamily, is reported to inhibit the growt...
BACKGROUND: GDF11 modulates embryonic patterning and kidney organogenesis. Herein, we sought to d...
BACKGROUND: Growth differentiation factor-9 (GDF9), a member of the bone morphogenetic protein (B...
Background: Growth and differentiation factor-9 (GDF9) is a member of the bone morphogentic protein ...
BACKGROUND: Growth and differentiation factor-9 (GDF9) is a member of the bone morphogentic protein...
Growth differentiation factor-9 (GDF-9) is a family member of bone morphogenetic proteins (BMPs), wh...
The role of bone morphogenetic proteins in the progression and metastasis of prostate cancer is a to...
Bone morphogenetic proteins (BMPs) have long been implicated in the process of prostate cancer progr...
As the most common malignant tumor of the urinary system worldwide, the bladder tumor has a high mor...
Both endogenous and exogenous GDF-9 led to a promotion in prostate cancer cell adhesion, invasion, m...
belong to the Transforming Growth Factor (TGF)-β superfamily and, besides their well-documented role...
Apillary () and chromophobe () renal cell carcinoma with strong ADAM9 expression. Normal renal tissu...
Kidney cancer of the clear cell type is often lethal and causes more than 100,000 deaths worldwide e...
The majority of advanced prostate cancers metastasise to the bone. Mediators of bone remodelling, th...
OBJECTIVE: To analyze the role of the transforming growth factor (TGF)-beta pathway in renal tumor...
Bone morphogenetic protein 9 (BMP9), a member of TGF-β superfamily, is reported to inhibit the growt...
BACKGROUND: GDF11 modulates embryonic patterning and kidney organogenesis. Herein, we sought to d...
BACKGROUND: Growth differentiation factor-9 (GDF9), a member of the bone morphogenetic protein (B...
Background: Growth and differentiation factor-9 (GDF9) is a member of the bone morphogentic protein ...
BACKGROUND: Growth and differentiation factor-9 (GDF9) is a member of the bone morphogentic protein...
Growth differentiation factor-9 (GDF-9) is a family member of bone morphogenetic proteins (BMPs), wh...
The role of bone morphogenetic proteins in the progression and metastasis of prostate cancer is a to...
Bone morphogenetic proteins (BMPs) have long been implicated in the process of prostate cancer progr...
As the most common malignant tumor of the urinary system worldwide, the bladder tumor has a high mor...
Both endogenous and exogenous GDF-9 led to a promotion in prostate cancer cell adhesion, invasion, m...
belong to the Transforming Growth Factor (TGF)-β superfamily and, besides their well-documented role...
Apillary () and chromophobe () renal cell carcinoma with strong ADAM9 expression. Normal renal tissu...
Kidney cancer of the clear cell type is often lethal and causes more than 100,000 deaths worldwide e...
The majority of advanced prostate cancers metastasise to the bone. Mediators of bone remodelling, th...
OBJECTIVE: To analyze the role of the transforming growth factor (TGF)-beta pathway in renal tumor...
Bone morphogenetic protein 9 (BMP9), a member of TGF-β superfamily, is reported to inhibit the growt...
BACKGROUND: GDF11 modulates embryonic patterning and kidney organogenesis. Herein, we sought to d...