Investigation of risk factors between hyperinsulinism and cardiovascular disease

目的 探讨高胰岛素血症(HIns)与心血管病危险因素的关系.方法 对100名高胰岛素血症组患者的腰围、体重指数、空腹血糖、血脂及临床患病情况进行分析,并与同期对照组130名胰岛素正常的人的各项指标进行比较.结果 HIns组的腰围(WC)、体重指数(BMI)、空腹血糖(FBG)、三酰甘油(TG)、高密度脂蛋白(HDL)明显高于对照组(P<0.01),肥胖、高血压、糖尿病、血脂异常、高血压合并糖尿病、高血压合并血脂异常、糖尿病合并血脂异常及肥胖合并高血压发生率也明显高于对照组(P<0.01).结论 高胰岛素血症与心血管病危险因素密切相关,各种心血管病危险因素不是独立存在而是彼此相关的.[Objective] To investigate the relationship between hyperinsulinism (HIS) and risk factors of cardio-vascular disease. [Methods] Waist circumference(WC), body mass index (BMI), fasting blood glucose(FBG), blood lipids and clinical illness were analyzed in 100 patients with hyperinsulinemia, and compared with 130 normal people in the same period. [Result] Compared with the contrasting group, WC, BMI, FBG, TG and HDL-C were significantly higher(P<0.01), morbidity rate of obesity, hypertension、dyslipidemia, diabetes, hypertension with diabetes, Hypertension with dyslipidemia, diabetes with dyslipidemia and obesity with hypertension were significantly higher, too(P <0.01). [Conclusion] HIns is closely correlated with the risk factors of cardiovascular disease . Every kind of risk factor in cardiovascular disease does not exist independently but is interrelated.中文核心期刊要目总览(PKU)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)0193029-30311