Add to ORKGβ肾上腺素受体(β-AR)除了通过经典的信号途径介导细胞生物功能外,还可以激活丝裂原活化蛋白激酶(MAPK)信号途径,活化后的MAPK参与调节多种细胞生物学活动.然而,将β-AR与MAPK信号联系起来的分子机制还需要进一步的研究.国家自然科学基金; 北京大学校科研和教改项目中文核心期刊要目总览(PKU)中国科学引文数据库(CSCD)02111-1143
目的研究有丝分裂原激活蛋白激酶(MAPK)信号传导通路在三苯氧胺(TAM)非雌激素拮抗的抗肿瘤机制中发挥的作用.方法应用TAM与MEK抑制剂PD98059处理MCF-7细胞,用Western 印迹法检...
Mitogen Activated Protein Kinases (MAPKs) are a conserved family of enzymes that form distinct signa...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
目的本研究检测了肝癌和癌旁肝组织中ERK1、ERK2、JNK1、p38及其上游MEK1、MEK2的蛋白表达量.方法手术切除16例肝癌及癌旁肝组织标本,Western印迹检测ERK1、ERK2、JNK1...
研究代表者研究分担者研究分担者研究分担者publisher研究種目：基盤研究（B）; 研究期間：2007～2010; 課題番号：19390024; 研究分野：細胞内情報伝達、ゲノム薬理; ...
目的:探讨细胞因子对血小板生成素(thrombopoietin,TPO)及其受体表达水平的调控方式.方法:Feulgen染色结合图像分析测定HEL细胞DNA含量的变化,细胞传感器检测TPO与其受体MP...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Activation of the mitogen activated protein kinase (MAPK) plays esential roles in many signal transd...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Cellular processes such as proliferation, apoptosis and differentiation are the basis for normal cel...
Cellular processes such as proliferation, apoptosis and differentiation are the basis for normal cel...
Regulation of cyclin D1 expression and cell cycle progression by mitogen-activated protein kinase ca...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Mitogen-activated protein kinases (MAPKs) are members of a dynamic protein kinase network through wh...
The mitogen-activated protein kinases (MAPKs) are a system of enzymes that form distinct signaling c...
目的研究有丝分裂原激活蛋白激酶(MAPK)信号传导通路在三苯氧胺(TAM)非雌激素拮抗的抗肿瘤机制中发挥的作用.方法应用TAM与MEK抑制剂PD98059处理MCF-7细胞,用Western 印迹法检...
Mitogen Activated Protein Kinases (MAPKs) are a conserved family of enzymes that form distinct signa...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
目的本研究检测了肝癌和癌旁肝组织中ERK1、ERK2、JNK1、p38及其上游MEK1、MEK2的蛋白表达量.方法手术切除16例肝癌及癌旁肝组织标本,Western印迹检测ERK1、ERK2、JNK1...
研究代表者研究分担者研究分担者研究分担者publisher研究種目：基盤研究（B）; 研究期間：2007～2010; 課題番号：19390024; 研究分野：細胞内情報伝達、ゲノム薬理; ...
目的:探讨细胞因子对血小板生成素(thrombopoietin,TPO)及其受体表达水平的调控方式.方法:Feulgen染色结合图像分析测定HEL细胞DNA含量的变化,细胞传感器检测TPO与其受体MP...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Activation of the mitogen activated protein kinase (MAPK) plays esential roles in many signal transd...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Cellular processes such as proliferation, apoptosis and differentiation are the basis for normal cel...
Cellular processes such as proliferation, apoptosis and differentiation are the basis for normal cel...
Regulation of cyclin D1 expression and cell cycle progression by mitogen-activated protein kinase ca...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...
Mitogen-activated protein kinases (MAPKs) are members of a dynamic protein kinase network through wh...
The mitogen-activated protein kinases (MAPKs) are a system of enzymes that form distinct signaling c...
目的研究有丝分裂原激活蛋白激酶(MAPK)信号传导通路在三苯氧胺(TAM)非雌激素拮抗的抗肿瘤机制中发挥的作用.方法应用TAM与MEK抑制剂PD98059处理MCF-7细胞,用Western 印迹法检...
Mitogen Activated Protein Kinases (MAPKs) are a conserved family of enzymes that form distinct signa...
Mitogen-activated protein kinase (MAPK) modules play key roles in the transduction of environmental ...