Correlation between Endometriosis and Other Benign Gynecological Diseases

目的：探讨子宫内膜异位症（endometriosis，EM）与其它妇科疾病的相关性，为EM诊治提供依据。方法回顾分析2005年7月~2009年6月北京大学第一临床医学院妇产科的妇科盆腔手术病例资料。对EM与妇科疾病的相关因素进行分析。结果①EM与其它妇科疾病相比，患者年龄较轻、初潮年龄较早、月经周期较短、经期较长、痛经及不孕人数较多、术中出血较多，且多合并子宫腺肌病，差异有统计学意义(P<0.05)。②痛经为EM的独立危险因素。③子宫肌瘤合并 EM者，年龄较轻、初潮年龄较早，痛经、不孕者较多；产次及人流次数较少。④子宫腺肌病合并EM者，年龄较轻、初潮年龄较早、未孕未产者较多。⑤其他子宫、卵巢、输卵管良性疾病合并EM者，痛经人数显著增多。结论①EM最常合并子宫腺肌病；②痛经为子宫内膜异位症的独立危险因素。Objective: To determine the correlation between endometriosis and other benign gynecological diseases. Methods: A retrospective study of patients who received pelvic surgeries in Obstetric & Gynecology department of Peking University first hospital during Jul. 1,2005 to Jun. 30,2009. Identifying the related factors between endometriosis and other benign gynecological diseases. Results:(1) Compared with other gynecologic diseases,patients with endometriosis are more younger, having earlier age at menarche,shorter menstrual cycle,longer period,more dysmenorrhea,infertility and bleeding. Moreover,patients with endometriosis are more common accompanying with adenomyosis (P<0.05). (2) Multivariate logistic regression demonstrates that dysmenorrhea is the risk factor of endometriosis. (3) Compared with leiomyomas,uterine fibroids with endometriosis are younger and having earlier age at menarche,and more dysmenorrhea and infertility. (4) Compared with adenomyosis, endometriosis with adenomyosis is younger and having earlier age at menarche,but patients with adenomyosis have shorter menstrual cycle,longer period and longer menstruation. (5) Other benign gynecological diseases with endometriosis, dysmenorrhea is the most common point. Conclusion:(1) Endometriosis is highly correlated with adenomyosis. (2) Dysmenorrhea is an independent risk factor of endometriosis.01133-13