Relationship Between Early Atherosclerosis and Dietary Nutrients Intake

目的：探讨早期动脉粥样硬化（Atherosclerosis,AS）与膳食营养素摄入量的相关性。方法 ：募集符合项目要求的45—65岁受试对象200名,采用多普勒彩色超声诊断仪检测受试对象颈总动脉内中膜厚度并观察有无斑块,依诊断标准将受试对象分为早期动脉粥样硬化组与正常对照组,并对其进行3d 24h膳食回顾调查。结果 ：早期AS组人群的能量、蛋白质、脂肪和碳水化合物摄入量均高于对照组,但组间比较未见统计学差异;早期AS组与正常组受试对象蛋白质、脂肪与碳水化合物的供能比分别为20.7%、22.4%、54.8%和21.3%、22.9%、53.1%;其它营养素摄入组间未见统计学差异。采用后退法进行多因素Logistic回归分析结果显示,K摄入量与早期动脉粥样硬化发生呈负相关。结论：膳食营养素K是早期动脉粥样硬化的保护因素,通过健康教育倡导合理营养和均衡膳食,以预防动脉粥样硬化的发生及延缓其进展。[Objective ] To investigate the relationship between early atherosclerosis and dietary nutrients intake. [Method] A total of 200 subjects 45--65 years old were recruited from a community in Beijing. Common carotid intima-media thickness was measured by carotid ultrasonography, and all subjects were asked to complete 24h recall dietary survey. [Result ] The intake of energy, protein, fat, and carbohydrate in atherosclerosis cases was higher than that in control group, however, there was no significant difference between the groups. The energy ratio of 3 yielding nutrients in 2 groups were 20. 7% , 22. 4% , 54. 8% and 21.3% , 22. 9% , 53. 1% , respectiiely. In Logistic Regression Model, thiamine was positively correlated with early atherosclerosis, while the intake of K was negatively correlated. [Conclusion] Risk factor and protective factor in dietary were simultaneously in the community population, and healthy dietary and balance nutrition should be advocated to prevent early atherosclerosis related cardiovascular diseases.国家自然科学基金中国科技核心期刊(ISTIC)0183-851