Two new quinoline glycoalkaloids from Echinops gmelinii

Two new glycosidic quinoline alkaloids, 1-methyl-4-methoxy-8-(beta-D-glucopyranosyloxy)-2(1H )-quinolinone ( 1 ) and 4-methoxy-8-(beta-D-glucopyranosyloxy)-2(1 H )-quinolinone ( 2 ), have been isolated from the 1-butanol extract of the aerial parts of Echinops gmelinii (Compositae). Structural elucidation of the two new glycoalkaloids was based on their H-1, C-13, DEPT, HSQC, COSY, HMBC NMR spectra and high-resolution FAB-MS data. These two compounds are rare examples of quinoline alkaloidal glycosides from natural sources.Plant SciencesChemistry, AppliedChemistry, MedicinalPharmacology & PharmacySCI(E)5ARTICLE3223-227