3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design (vol 355, pg 513, 2007)

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30

Louet, Maxime
Labbé, Céline M.
Fagnen, Charline
Aono, Cassiano,
Homem-de-Mello, Paula
Villoutreix, Bruno,
Miteva, Maria,

January 2018

International audienceCytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated...

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30.

Maxime Louet
Céline M Labbé
Charline Fagnen
Cassiano M Aono
Paula Homem-de-Mello
Bruno O Villoutreix
Maria A Miteva

January 2018

Cytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated drugs. The allelic va...

Structural Models for Cytochrome P450�Mediated Catalysis

David F.V. Lewis

January 2003

This review focuses on the structural models for cytochrome P450 that are improving our knowledge an...

3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design (vol 355, pg 513, 2007)

Wang, Jing-Fang
Wei, Dong-Qing
Li, Lin
Zheng, Si-Yuan
Li, Yi-Xue
Chou, Kuo-Chen

January 2009

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAM...

3D structure modeling of cytochrome P4502C19 and its implication for personalized drug design

Wang, Jing-Fang
Wei, Dong-Qing
Li, Lin
Zheng, Si-Yuan
Li, Yi-Xue
Chou, Kuo-Chen

January 2007

Cytochrome P450 2C19 (CYP209) is a member of the cytochrome P-450 enzyme superfamily and plays an im...

Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6

Kirton, S.B.
Sutcliffe, M.J.
Kemp, C.A.
Tomkinson, N.P.
St-Gallay, S.

November 2002

MEDLINE® is the source for the MeSH terms of this document.Cytochrome P450 2D6 (CYP2D6) metabolizes ...

MODELLING OF P450 ACTIVE SITE BASED ON CONSENSUS 3D STRUCTURES

Jean-christophe Nebel

December 2014

P450 enzymes constitute a large superfamily of haem-thiolate proteins involved in the metabolism of ...

Comparative modelling of cytochromes P450

Kirton, S. B.
Baxter, C. A.
Sutcliffe, M. J.

March 2002

The superfamily of enzymes known as the cytochromes P450 (P450s) comprises a wide-ranging class of p...

Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions

Marechal, J-D
Kemp, C. A.
Roberts, G. C. K.
Paine, Mark
Wolf, Roland
Sutcliffe, M. J.

March 2008

The cytochromes P450 ( CYPs) comprise a vast superfamily of enzymes found in virtually all life form...

A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, P450 102, and P450 108.

de Groot, M.J.
Vermeulen, N.P.E.
Kramers, J.D.
van Acker, F.A.A.
Donné-Op den Kelder, G.M.

January 1996

Cytochromes P450 (P450s) constitute a superfamily of phase I enzymes capable of oxidizing and reduci...

A preliminary 3D model for cytochrome P450 2D6 constructed by homology model building

Koymans, L M
Vermeulen, N P
Baarslag, A
Donné-Op den Kelder, G M

June 1993

A homology model building study of cytochrome P450 2D6 has been carried out based on the crystal str...

Construction of a 3D model of cytochrome P450 2B4

Chang, Yan-Tyng
Stiffelman, Oscar B.
Vakser, Ilya A.
Loew, Gilda H.
Bridges, Angela
Waskell, Lucy

February 1997

This is the publisher's version, also available electronically from "http://peds.oxfordjournals.org"...

Computational studies of the cytochromes P450

Stewart Brian. Kirton (7669370)

January 2002

Validation of standard comparative modelling techniques was carried out by comparison between severa...

Discerning Relationships Among Human Cytochrome P450s by Computational Analyses

Alok Juneja
Kulvinder Singh Saini
Rajeev Soni

August 2015

Cytochrome P450s are involved in the biotransformations and metabolism of wide variety of xenobiotic...

Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors

Zbigniew Dutkiewicz
Renata Mikstacka

January 2018

Cytochromes P450 are a class of metalloproteins which are responsible for electron transfer in a wid...

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30

Louet, Maxime
Labbé, Céline M.
Fagnen, Charline
Aono, Cassiano,
Homem-de-Mello, Paula
Villoutreix, Bruno,
Miteva, Maria,

January 2018

International audienceCytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated...

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30.

Maxime Louet
Céline M Labbé
Charline Fagnen
Cassiano M Aono
Paula Homem-de-Mello
Bruno O Villoutreix
Maria A Miteva

January 2018

Cytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated drugs. The allelic va...

Structural Models for Cytochrome P450�Mediated Catalysis

David F.V. Lewis

January 2003

This review focuses on the structural models for cytochrome P450 that are improving our knowledge an...

3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design (vol 355, pg 513, 2007)

Wang, Jing-Fang
Wei, Dong-Qing
Li, Lin
Zheng, Si-Yuan
Li, Yi-Xue
Chou, Kuo-Chen

January 2009

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAM...

3D structure modeling of cytochrome P4502C19 and its implication for personalized drug design

Wang, Jing-Fang
Wei, Dong-Qing
Li, Lin
Zheng, Si-Yuan
Li, Yi-Xue
Chou, Kuo-Chen

January 2007

Cytochrome P450 2C19 (CYP209) is a member of the cytochrome P-450 enzyme superfamily and plays an im...

Impact of incorporating the 2C5 crystal structure into comparative models of cytochrome P450 2D6

Kirton, S.B.
Sutcliffe, M.J.
Kemp, C.A.
Tomkinson, N.P.
St-Gallay, S.

November 2002

MEDLINE® is the source for the MeSH terms of this document.Cytochrome P450 2D6 (CYP2D6) metabolizes ...

MODELLING OF P450 ACTIVE SITE BASED ON CONSENSUS 3D STRUCTURES

Jean-christophe Nebel

December 2014

P450 enzymes constitute a large superfamily of haem-thiolate proteins involved in the metabolism of ...

Comparative modelling of cytochromes P450

Kirton, S. B.
Baxter, C. A.
Sutcliffe, M. J.

March 2002

The superfamily of enzymes known as the cytochromes P450 (P450s) comprises a wide-ranging class of p...

Insights into drug metabolism by cytochromes P450 from modelling studies of CYP2D6-drug interactions

Marechal, J-D
Kemp, C. A.
Roberts, G. C. K.
Paine, Mark
Wolf, Roland
Sutcliffe, M. J.

March 2008

The cytochromes P450 ( CYPs) comprise a vast superfamily of enzymes found in virtually all life form...

A three-dimensional protein model for human cytochrome P450 2D6 based on the crystal structures of P450 101, P450 102, and P450 108.

de Groot, M.J.
Vermeulen, N.P.E.
Kramers, J.D.
van Acker, F.A.A.
Donné-Op den Kelder, G.M.

January 1996

Cytochromes P450 (P450s) constitute a superfamily of phase I enzymes capable of oxidizing and reduci...

A preliminary 3D model for cytochrome P450 2D6 constructed by homology model building

Koymans, L M
Vermeulen, N P
Baarslag, A
Donné-Op den Kelder, G M

June 1993

A homology model building study of cytochrome P450 2D6 has been carried out based on the crystal str...

Construction of a 3D model of cytochrome P450 2B4

Chang, Yan-Tyng
Stiffelman, Oscar B.
Vakser, Ilya A.
Loew, Gilda H.
Bridges, Angela
Waskell, Lucy

February 1997

This is the publisher's version, also available electronically from "http://peds.oxfordjournals.org"...

Computational studies of the cytochromes P450

Stewart Brian. Kirton (7669370)

January 2002

Validation of standard comparative modelling techniques was carried out by comparison between severa...

Discerning Relationships Among Human Cytochrome P450s by Computational Analyses

Alok Juneja
Kulvinder Singh Saini
Rajeev Soni

August 2015

Cytochrome P450s are involved in the biotransformations and metabolism of wide variety of xenobiotic...

Structure-Based Drug Design for Cytochrome P450 Family 1 Inhibitors

Zbigniew Dutkiewicz
Renata Mikstacka

January 2018

Cytochromes P450 are a class of metalloproteins which are responsible for electron transfer in a wid...

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30

Louet, Maxime
Labbé, Céline M.
Fagnen, Charline
Aono, Cassiano,
Homem-de-Mello, Paula
Villoutreix, Bruno,
Miteva, Maria,

January 2018

International audienceCytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated...

Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30.

Maxime Louet
Céline M Labbé
Charline Fagnen
Cassiano M Aono
Paula Homem-de-Mello
Bruno O Villoutreix
Maria A Miteva

January 2018

Cytochrome P450 2C9 (CYP2C9) metabolizes about 15% of clinically administrated drugs. The allelic va...

Structural Models for Cytochrome P450�Mediated Catalysis

David F.V. Lewis

January 2003

This review focuses on the structural models for cytochrome P450 that are improving our knowledge an...

3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design (vol 355, pg 513, 2007)

Abstract

Extracted data

3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design (vol 355, pg 513, 2007)

Abstract

Extracted data

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