目的探讨己烯雌酚对BALB/c小鼠胸腺内雌激素受体水平的影响.方法新生小鼠分为实验组与对照组,连续5天皮下注射己烯雌酚,7周后取其胸腺进行雌激素受体免疫组织化学反应及图像分析.结果己烯雌酚可以提高实验组小鼠胸腺内雌激素受体水平,2组间有显著性差异.结论雌激素对胸腺的作用主要是通过雌激素受体来进行,新生期接触雌激素对胸腺内雌激素受体水平的影响会持续到成年期.面向21世纪教育振兴行动计划(985计划)05377-3792
Diethylstilbestrol (DES) is a synthetic estrogen used in the United States from 1938-1971 for the pr...
2007-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号:19530659 研究代表者:富原一哉 (鹿児島大学法文学部教授)妊娠期の内分泌かく乱が母性発現へ及ぼす影響を検討する...
ABSTRACT-The effects of ovariectomy at 1 month of age and continuous 17~-estradiol (E2) and/or proge...
目的 了解新生期注射己烯雌酚(DES)后雌性BALB/c小鼠脾内细胞雌激素受体表达的动态变化.方法 雌性BALB/c小鼠在生后24h内,颈背部皮下注射DES,每隔34h注射1次,共连续注射5次.对照组...
目的:研究围生期双酚A(Bisphenol A,BPA)暴露对SD大鼠子代生殖系统的影响及雌激素受体(Estrogen Receptor,ER)表达的改变.方法:经灌胃给予围生期孕鼠O、5、50、50...
了解雌激素受体(ER)在不同周龄雌性BALB/c小鼠胸腺中的表达.结果显示从出生后1周至8周,ER在胸腺中的表达量逐渐增加.ER阳性细胞为胸腺上皮细胞和胸腺细胞.ER既存在于胞质,也存在于胞核.中文核...
目的 了解新生期注射己烯雌酚(diethylstilbestrol,DES)对雌性BALB/c小鼠生后不同时期脾细胞凋亡及Bcl-2、Bax的影响.方法 新生雌性BALB/c小鼠,在生后24h内颈背部...
目的探讨雌激素受体(ER)在大鼠大脑神经元及神经胶质细胞表达的增龄性变化.方法采用免疫组织化学方法观察不同年龄正常组及脑损伤组SD大鼠脑内ER的表达变化并行统计学分析.结果正常老年组海马齿状回神经元E...
Abstract only availableFaculty Mentor: Dr. Frederick vomSaal, BiologyWe examined the effect of mater...
International audienceNatural and synthetic estrogens, Including diethylstilbestrol (DES), given dur...
The effect of neonatal exposure to diethylstilbestrol (DES), a potent synthetic estrogen, was examin...
AbstractData indicate that estrogen-dependent and -independent pathways are involved in the teratoge...
Many of the tumorigenic effects that result from neonatal exposure to both natural and synthetic est...
Neonatal exposure to estrogenic chemicals causes irreversible complex damage to the hypothalamus–pit...
ABSTRACT-Neonatal female NMRI mice were given Injections of olive 011 (controls) or dally doses of c...
Diethylstilbestrol (DES) is a synthetic estrogen used in the United States from 1938-1971 for the pr...
2007-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号:19530659 研究代表者:富原一哉 (鹿児島大学法文学部教授)妊娠期の内分泌かく乱が母性発現へ及ぼす影響を検討する...
ABSTRACT-The effects of ovariectomy at 1 month of age and continuous 17~-estradiol (E2) and/or proge...
目的 了解新生期注射己烯雌酚(DES)后雌性BALB/c小鼠脾内细胞雌激素受体表达的动态变化.方法 雌性BALB/c小鼠在生后24h内,颈背部皮下注射DES,每隔34h注射1次,共连续注射5次.对照组...
目的:研究围生期双酚A(Bisphenol A,BPA)暴露对SD大鼠子代生殖系统的影响及雌激素受体(Estrogen Receptor,ER)表达的改变.方法:经灌胃给予围生期孕鼠O、5、50、50...
了解雌激素受体(ER)在不同周龄雌性BALB/c小鼠胸腺中的表达.结果显示从出生后1周至8周,ER在胸腺中的表达量逐渐增加.ER阳性细胞为胸腺上皮细胞和胸腺细胞.ER既存在于胞质,也存在于胞核.中文核...
目的 了解新生期注射己烯雌酚(diethylstilbestrol,DES)对雌性BALB/c小鼠生后不同时期脾细胞凋亡及Bcl-2、Bax的影响.方法 新生雌性BALB/c小鼠,在生后24h内颈背部...
目的探讨雌激素受体(ER)在大鼠大脑神经元及神经胶质细胞表达的增龄性变化.方法采用免疫组织化学方法观察不同年龄正常组及脑损伤组SD大鼠脑内ER的表达变化并行统计学分析.结果正常老年组海马齿状回神经元E...
Abstract only availableFaculty Mentor: Dr. Frederick vomSaal, BiologyWe examined the effect of mater...
International audienceNatural and synthetic estrogens, Including diethylstilbestrol (DES), given dur...
The effect of neonatal exposure to diethylstilbestrol (DES), a potent synthetic estrogen, was examin...
AbstractData indicate that estrogen-dependent and -independent pathways are involved in the teratoge...
Many of the tumorigenic effects that result from neonatal exposure to both natural and synthetic est...
Neonatal exposure to estrogenic chemicals causes irreversible complex damage to the hypothalamus–pit...
ABSTRACT-Neonatal female NMRI mice were given Injections of olive 011 (controls) or dally doses of c...
Diethylstilbestrol (DES) is a synthetic estrogen used in the United States from 1938-1971 for the pr...
2007-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号:19530659 研究代表者:富原一哉 (鹿児島大学法文学部教授)妊娠期の内分泌かく乱が母性発現へ及ぼす影響を検討する...
ABSTRACT-The effects of ovariectomy at 1 month of age and continuous 17~-estradiol (E2) and/or proge...