New routes for the synthesis of fused pyrrole scaffolds through transition metal-free tandem reactions

Yang, Bingchuan
Huang, Zixiao
Guan, Hegen
Niu, Xiaoyi
Li, Yanqiu
Fang, Shuai
Ma, Chen

Open link

Publication date

January 2013

DOI

10.1016/j.tetlet.2013.08.060

Publisher

四面体通讯

ISSN

0040-4039

Journal

issn:0040-4039

Citation count (estimate)

Abstract

A series of transition metal-free tandem reactions for the synthesis of indolizines and 6,7-dihydroindolizin-8(5H)-ones by 4-bromobut-2-enoate ramifications reacted with 2-acetyl pyrrole derivatives are described. As the alpha-carbon changed from CH3, CH2Cl, CHCl2, to CCl3, different kinds of tandem reactions were observed. These tandem reactions could be used to synthesize fused indolizine and indolizidine scaffolds under mild and green conditions. (C) 2013 Elsevier Ltd. All rights reserved.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000325736300014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Chemistry, OrganicSCI(E)10ARTICLE455994...

Extracted data

We use cookies to provide a better user experience.

Data Protection

New routes for the synthesis of fused pyrrole scaffolds through transition metal-free tandem reactions

Abstract

Extracted data

New routes for the synthesis of fused pyrrole scaffolds through transition metal-free tandem reactions

Abstract

Extracted data

Related items

Related items