A bibliometric analysis was conducted to evaluate the global scientific output of proteomics research in the Science Citation Index Expanded from 1995 to 2010. The document types, languages, journals, categories, countries, and institutions were analyzed to obtain publication patterns. Research focuses and trends were revealed by a word cluster method related to author keywords, title, abstract, and KeyWords Plus. Bradford's Law and the correlation between keywords and institutions were identified to look deeper into the nature works. Proteomics and Journal of Proteome Research published the most articles in proteomics research. The researchers focused on the categories of biochemical research methods, and biochemistry and molecular bi...