The effects of maternal aging on the localization of DNA methyltransferases were evaluated during mouse oocyte maturation using fluorescence staining. And we conclude that maternal aging affects the cytoplasmic-to-nuclear trafficking of DNA methyltransferases in mouse oocytes during the time from germinal vesicle breakdown to metaphase I. (Fertil Steril (R) 2011;95:1531-4. (C) 2011 by American Society for Reproductive Medicine.)Obstetrics & GynecologyReproductive BiologySCI(E)PubMed5EDITORIAL MATERIAL41531-U3939
Meiotic division of a female germ cell, an oocyte, is more prone to segregation errors and consequen...
Aneuploidy arising from chromosome segregation errors in female meiosis is a leading genetic cause o...
Tatone C., Carbone M., Heizenrieder T., Gualtieri R., Eichenlaub-Ritter U. Mechanisms underlying ag...
This paper investigated the age-related changes in the expression patterns of maintenance methyltran...
The rate of chromosome segregation errors that emerge during meiosis I in the mammalian female germ ...
Decreasing oocyte competence with maternal aging is a major factor in human infertility. To investig...
Female reproductive ageing is associated with oocyte quality decline and increased risk of maternofo...
DNA methylation is the most widely investigated epigeneticmodification associated with the repressio...
In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to inferti...
Eichenlaub-Ritter U, Staubach N, Trapphoff T. Chromosomal and cytoplasmic context determines predisp...
Immunofluorescence staining with antibodies against acetylated histone H4 and 5-methylcytosine was c...
Classical studies have shown that reproductive performance declines with maternal age in humans and ...
Trapphoff T, Heiligentag M, Dankert D, et al. Postovulatory aging affects dynamics of mRNA, expressi...
Tatone C, Heizenrieder T, Di Emidio G, et al. Evidence that carbonyl stress by methylglyoxal exposur...
Background In vitro follicle culture (IFC), as applied in the mouse system, allows the growth and m...
Meiotic division of a female germ cell, an oocyte, is more prone to segregation errors and consequen...
Aneuploidy arising from chromosome segregation errors in female meiosis is a leading genetic cause o...
Tatone C., Carbone M., Heizenrieder T., Gualtieri R., Eichenlaub-Ritter U. Mechanisms underlying ag...
This paper investigated the age-related changes in the expression patterns of maintenance methyltran...
The rate of chromosome segregation errors that emerge during meiosis I in the mammalian female germ ...
Decreasing oocyte competence with maternal aging is a major factor in human infertility. To investig...
Female reproductive ageing is associated with oocyte quality decline and increased risk of maternofo...
DNA methylation is the most widely investigated epigeneticmodification associated with the repressio...
In mammalian oocytes DNA damage can cause chromosomal abnormalities that potentially lead to inferti...
Eichenlaub-Ritter U, Staubach N, Trapphoff T. Chromosomal and cytoplasmic context determines predisp...
Immunofluorescence staining with antibodies against acetylated histone H4 and 5-methylcytosine was c...
Classical studies have shown that reproductive performance declines with maternal age in humans and ...
Trapphoff T, Heiligentag M, Dankert D, et al. Postovulatory aging affects dynamics of mRNA, expressi...
Tatone C, Heizenrieder T, Di Emidio G, et al. Evidence that carbonyl stress by methylglyoxal exposur...
Background In vitro follicle culture (IFC), as applied in the mouse system, allows the growth and m...
Meiotic division of a female germ cell, an oocyte, is more prone to segregation errors and consequen...
Aneuploidy arising from chromosome segregation errors in female meiosis is a leading genetic cause o...
Tatone C., Carbone M., Heizenrieder T., Gualtieri R., Eichenlaub-Ritter U. Mechanisms underlying ag...