Prospective study of Han's acupoint nerve stimulator for preventing relapse of detoxified heroin addicts

目的 观察韩氏穴位神经刺激仪(韩氏仪,HANS)对强制脱毒后的海洛因成瘾者发生复吸的影响.方法 对上海地区164例经历3个月到3年强制和劳教脱毒的海洛因成瘾者,给予3个月以上的韩氏仪治疗,并进行12个月的尿液吗啡检测及防复吸效果随访.结果 接受韩氏仪治疗的164例脱毒者,1年后有53例尿检全部呈现阴性(未复吸),35例在此过程中尿检转为阳性(复吸),76例脱失(视为复吸),总复吸率为67.7%,1年防复吸成功率为32.3%.同时显示,强制脱毒的期限长短与复吸率没有显著性关系.结论 与以往文献记载的强制脱毒后不给予干预措施的海洛因脱毒者其1年复吸率为95%以上比较,韩氏仪能够显著降低强制脱毒后处于康复期的海洛因脱毒者的复吸率.To assess the efficacy of transcutaneous electrical acupoint stimulation (TEAS) in preventing the relapse of detoxified heroin users in a period of 12 months.A total of 164 rehabilitating heroin users in Shanghai area were recruited after compulsory detoxification treatment for a period ranging from 3 months to 3 years. The TEAS was executed by the device named Han's acupoint nerve stimulator (HANS). The patients were treated with HANS for at least 3 months. All the subjects were then followed up for one year and relapse was monitored by monthly heroin/morphine urinalysis.Of 164 rehabilitating former heroin addicts, 53 remained drug-free at the end of 12 months observation period as judged by negative urinalysis while 35 become relapsed as documented by positive urine tests. The rest 76 dropped off due to various reasons and were all counted into the category of "relapsed". Thus, our data indicated 32.3% rehabilitating heroin users could stay sober for at least one year, which is significantly higher than the existing reports that less than 5% detoxified abusers would stay drug free for one year with no further intervention. No obvious correlation was found between the susceptibility of relapse and the duration of compulsory detoxification.Compared to the existing literatures, our results indicate that HANS could produce a marked decrease of the relapse rate of rehabilitating heroin users after compulsory detoxification.上海市科学技术委员会基金; 吴阶平医学基金会基金; 国家科技支撑计划PubMed中文核心期刊要目总览(PKU)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)0211472-14769