Palladium-Catalyzed Trifluoromethylation of Aromatic C-H Bond Directed by an Acetamino Group
- Zhang, Li-Sheng
- Chen, Kang
- Chen, Guihua
- Li, Bi-Jie
- Luo, Shuang
- Guo, Qing-Yun
- Wei, Jiang-Bo
- Shi, Zhang-Jie
DOIAbstract
The first palladium-catalyzed ortho-trifluoromethylation of the aromatic C-H bond directed by an acetamino group is reported. This method provides an efficient and green approach to synthesize the highly biological potential key structure of ortho-CF3 acetanilides and anilines.Chemistry, OrganicSCI(E)PubMed47ARTICLE110-131
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