New therapeutic approach for Alzheimer disease

The amyloid β-protein (Aβ) 42 plays a pivotal role in Alzheimer disease (AD). We have previously reported that intracellular Aβ42 is associated with neuronal apoptosis (Chui et al, 1999, Chui et al, 2001). AD may be caused by toxic aggregates formed from Aβpeptides. By using Thioflavin T, a dye t...