The impact of surgical sperm retrieval on the in vitro fertilization outcomes of infertile patients with temporary ejaculation failure on their oocyte retrieval day

Objective: To evaluate the impact of testicular sperm aspiration on the clinical outcomes of IVF patients with temporary ejaculation failure (TEF) on the day of oocyte retrieval. Design: A case-control study. Setting: University-affiliated IVF center. Patient(s): One hundred eight infertile couples encountering TEF on the day of oocyte retrieval. Intervention(s): Testicular sperm aspiration and intracytoplasmic sperm injection (TESA-ICSI) were employed to help the TEF couples to complete their IVF treatments. A group of obstructive azoospermia (OA) patients was chosen as a control group to evaluate the efficiency and safety of this intervention. Main Outcome Measure(s): Fertilization rates, transferable embryo rates, and clinical pregnancy rates (PRs). Result(s): Through the TESA-ICSI, TEF couples achieved a 38.83% (40/103) clinical PR per IVF cycle. Compared with the OA group, the TEF group showed a comparable fertilization rate (66.43% vs. 65.25%), transferable embryo rate (60.76% vs. 60.85%), and PR (51.61% vs. 50.00%) in thawed ET cycles but a relatively low PR (25.49% vs. 44.64%) in fresh ET cycles. Conclusion(s): TESA-ICSI is a relatively efficient and safe way to help the patients encountering TEF. (Fertil Steril (R) 2013;99:362-6. (C) 2013 by American Society for Reproductive Medicine.)http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000314662400017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Obstetrics & GynecologyReproductive BiologySCI(E)PubMed0ARTICLE2362-3669