In situ mechanical analysis of cardiomyocytes at nano scales

Liu, Yuansheng
Feng, Jiantao
Shi, Liang
Niu, Ruibin
Sun, Quanmei
Liu, Hao
Li, Jing
Guo, Jihong
Zhu, Jihong
Han, Dong

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Publication date

January 2012

DOI

10.1039/c1nr11303h

Publisher

nanoscale

ISSN

2040-3364

Journal

issn:2040-3364

Abstract

Nanomechanical behaviors of single living cardiomyocytes are quantitatively observed using calculated torsions and deflections of an AFM cantilever. The lateral contractions are related to the calcium intensity within rather than the vertical beating power of the cardiomyocytes. Drug-induced nanomechanical changes of cardiomyocytes were further investigated by measuring lateral contractions in real time.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297848500009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701Chemistry, MultidisciplinaryNanoscience & NanotechnologyMaterials Science, MultidisciplinaryPhysics, AppliedSCI(E)EIPubMed...

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In situ mechanical analysis of cardiomyocytes at nano scales

Abstract

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In situ mechanical analysis of cardiomyocytes at nano scales

Abstract

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