New coumarin glycosides from the leaves of Diospyros crassiflora (Hiern)
- Akak, Carine Mvot
- Djama, Celine Mbazoa
- Nkengfack, Augustin Ephrem
- Tu, Peng-Fei
- Lei, Lian-Di
DOIAbstract
Two new 5-methylcoumarin glycosides named diosfeboside A (1) and B (2) and five known compounds namely kaempferol 3-O-alpha-L-rhamnopyranosyl-(1 -> 2)-beta-D-glucopyranoside (3), ursolic acid (4), betulinic acid (5), stigmasterol (6) and stigmasterol 3-O-beta-D-glucopyranoside (7) were isolated from the leaves of Diospyros crassiflora (Hiern). Their structures were established through interpretation of 1 and 2D NMR, mass spectra analysis and comparison with reported data. In vitro cytotoxic activity of the new compounds against human carcinoma cell lines (HL-60, Bel-7402, BGC-823, and KB) was evaluated and no cytotoxicity was observed for each of them. (C) 2010 Elsevier B.V. All rights reserved.http://gateway.webofknowledge.com/gateway/G...
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