Formamidobisabolene-based derivatives from a sponge Axinyssa sp.

Cheng, Wei
Liu, Dong
Zhang, Fengying
Zhang, Qingying
Pedpradab, Patchara
Proksch, Peter
Liang, Hong
Lin, Wenhan

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Publication date

January 2014

DOI

10.1016/j.tet.2014.04.008

Publisher

tetrahedron

ISSN

0040-4020

Journal

issn:0040-4020

Citation count (estimate)

Abstract

Chemical examination of a Chinese sponge Axinyssa sp. resulted in the isolation of 12 new formamidobisabolene-based analogues named axinyssines A-L (1-12), along with a new natural product (13) and three known formamidobisabolenes (14-16). Their structures were determined on the basis of extensive NMR and mass spectroscopic analyses in association with ICD data, Mosher reaction and chemical conversion for the assignment of absolute configurations. All compounds were evaluated for antitumor and antimicrobial activities. (C) 2014 Elsevier Ltd. All rights reserved.http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000336868200006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=...

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Formamidobisabolene-based derivatives from a sponge Axinyssa sp.

Abstract

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Formamidobisabolene-based derivatives from a sponge Axinyssa sp.

Abstract

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