Total elbow arthroplasty after resection of tumors at the elbow

目的 探讨肘关节周围肿瘤切除术后行全肘关节成形术的疗效及并发症处理.方法 1998年6月至2007年6月,19例患者在北京大学人民医院接受了肿瘤切除后全肘关节置换术.其中男性13例,女性6例;转移癌6例,骨巨细胞瘤1例,恶性纤维组织细胞瘤(MFH)2例,骨肉瘤4例,尤文肉瘤3例,恶性淋巴瘤1例,滑膜肉瘤1例,骨的硬纤维瘤1例;年龄15～71岁,平均43岁;肱骨远端9例,尺骨近端5例,肱骨远端及尺骨近端均受累5例.结果 除1例失随访外,18例患者均至少随访1年或随访至死亡,平均随访时间37个月.根据Mayo评分标准,平均疼痛评分从3.6降至2.0.肘关节的平均屈伸范围由29°改善为73°(范围:55°～105°).14例患者手术效果优良(14/18,77.8%),4例患者手术效果可以接受(4/18,22.2%).尚无患者出现术后感染及伤口并发症.在随访期间,2例肺癌、1例直肠癌及1例卵巢癌骨转移患者均分别死于术后2年内.2例尤文肉瘤、1例MFH及1例骨肉瘤出现肺转移(4/18,22.2%),肿瘤局部复发2例(11.1%).3例患者术后随访中出现并发症(3/18,16.7%),1例患者术后5年出现肱骨假体柄穿出骨皮质,1例患者术后4年出现尺骨假体柄穿出骨皮质,2例均经设计较长假体柄行假体翻修术.1例患者术后4年出现肱骨假体柄松动,行假体翻修术后功能良好.结论 肿瘤切除后实施全肘关节成形术能够显著减轻疼痛,改善功能.转移瘤的患者,特别是其他方法 均不能缓解症状时,也可以采用这种手术方法.Objective To explore the effects and complications of the total elbow arthroplasty after the resection of the peri-elbow tumor. Methods Between June 1998 to June 2007, 19 patients underwent total elbow arthroplasty after resection of tumors at the authors department, which involved 13 males and 6 females, including 6 patients with metastatic tumor, 1 with giant cell tumor of bone (GCT), 2 with malignant fibrous histiocytoma (MFH), 4 with osteosacoma, 3 with Ewing sarcoma, 1 with lymphoma, 1 with synovial sarcoma, and 1 with desmoid fibroma of the bone. The age of patients ranged from 15 to 71 years (mean 43 years). Location: distal humerus in 9 cases, proximal ulna in 5 and the tumor involving both distal humerus and proximal ulna in 5 patients. Results Patients were evaluated according to the Mayo Elbow Performance Score. Pain scores decreased from a mean of 3.6 to 2.0. Mean arc of elbow motion from extention to flexision improved from 30 to 80 (range, 55-105). Fourteen elbows had excellent or good result (14/19, 77.8%), and 4 elbows had a poor result (22.2%). There was no wound infection or other complication after surgery. During the following up time, 2 patients with metastatic lung cancer, 1 with metastatic rectal cancer and 1 with ovarian cancer died in 2 years after surgery. Two Ewing sarcoma, 1 MFH and 1 osteosarcoma patients occurred lung metastasis(4/18,22.2%),and two patients had local recurrence (11.1%).Three patients occurred complication during the following time (3/18, 16.7%), the stem of humerus prosthesis came out of cannel in 1 case 5 years after surgery, the stem of ulna prosthesis came out of cannel in 1 case 4 years after surgery, and both cases did revision surgery. The stem loosening was in 1 humerus prosthesis 4 years after surgery. Conclusions The results show that total elbow arthroplasty after resection of tumors can decrease the pain, and improve the function substantially. For metastatic tumors, this technique also can be used if there is no other good option.中文核心期刊要目总览(PKU)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)0221734-17374