Add to ORKGRNA干扰(RNAi)是指生物体内由双链RNA介导同源序列mRNA的特异性降解,从而导致基因沉默的现象.近年来,随着对RNAi研究的不断深入,其作用机制正在逐步被阐明;同时作为阻断基因表达的新手段,RNAi技术也日趋完善和成熟.以其高效性和特异性,RNAi为反向遗传学在神经科学研究中的应用提供了有力的工具.本文仅就RNAi技术的有关研究进展及其在神经科学研究中的应用作一概述.国家自然科学基金05332-3361
Experimental RNA interference (RNAi) leading to the selective knockdown of gene function is induced ...
RNA interference (RNAi) is a gene silencing mechanism which is triggered by double stranded RNA. RNA...
The discovery of RNA interference (RNAi) gave rise to the development of new nucleic acid-based tech...
One of the most exciting findings in recent years has been the discovery of RNA interference (RNAi)....
RNA干扰(RNA interference,RNAi)是一种新兴的基因阻断技术,它通过双链RNA分子的介导,特异降解相应序列的mRNA,从而导致转录后水平的基因沉默,自1998年首次报道以来已取得了...
双链RNA(dsRNA)诱导与之同源的mRNA降解,从而导致转录后基因缄默(post-transcriptional gene silencing,PTGS)的现象或机制被称为RNA干扰(RNA in...
Over the past 20 years, RNA interference (RNAi) technology has provided a new regulatory paradigm in...
Psychiatric and neurological disorders are among the most complex, poorly understood, and debilitati...
RNAi interference (RNAi) is a powerful gene silencing technology that has immense potential for trea...
RNA interference (RNAi), a mediator of gene silencing, has swiftly become one of the most exciting a...
Antisense techniques are powerful tools for the inhibition of gene expression in the target discover...
RNA干扰技术(RNA interference,RNAi)通过向细胞内引人双链RNA介导同源靶向tnRNA特异性降解,最终导致转录后水平的基因沉默.RNAi现象是由Andrew Fire和Craig...
The post-genomic era has unveiled the existence of a large repertory of non-coding RNAs and repetiti...
目的:研究RNA干扰(RNA interference,RNAi)对皮肤鳞癌EGFR基因表达的抑制作用及其对A431细胞增殖、凋亡的影响。研究RNA干扰(RNA interference,RNAi)对...
Experimental RNA interference (RNAi) leading to the selective knockdown of gene function is induced ...
Experimental RNA interference (RNAi) leading to the selective knockdown of gene function is induced ...
RNA interference (RNAi) is a gene silencing mechanism which is triggered by double stranded RNA. RNA...
The discovery of RNA interference (RNAi) gave rise to the development of new nucleic acid-based tech...
One of the most exciting findings in recent years has been the discovery of RNA interference (RNAi)....
RNA干扰(RNA interference,RNAi)是一种新兴的基因阻断技术,它通过双链RNA分子的介导,特异降解相应序列的mRNA,从而导致转录后水平的基因沉默,自1998年首次报道以来已取得了...
双链RNA(dsRNA)诱导与之同源的mRNA降解,从而导致转录后基因缄默(post-transcriptional gene silencing,PTGS)的现象或机制被称为RNA干扰(RNA in...
Over the past 20 years, RNA interference (RNAi) technology has provided a new regulatory paradigm in...
Psychiatric and neurological disorders are among the most complex, poorly understood, and debilitati...
RNAi interference (RNAi) is a powerful gene silencing technology that has immense potential for trea...
RNA interference (RNAi), a mediator of gene silencing, has swiftly become one of the most exciting a...
Antisense techniques are powerful tools for the inhibition of gene expression in the target discover...
RNA干扰技术(RNA interference,RNAi)通过向细胞内引人双链RNA介导同源靶向tnRNA特异性降解,最终导致转录后水平的基因沉默.RNAi现象是由Andrew Fire和Craig...
The post-genomic era has unveiled the existence of a large repertory of non-coding RNAs and repetiti...
目的:研究RNA干扰(RNA interference,RNAi)对皮肤鳞癌EGFR基因表达的抑制作用及其对A431细胞增殖、凋亡的影响。研究RNA干扰(RNA interference,RNAi)对...
Experimental RNA interference (RNAi) leading to the selective knockdown of gene function is induced ...
Experimental RNA interference (RNAi) leading to the selective knockdown of gene function is induced ...
RNA interference (RNAi) is a gene silencing mechanism which is triggered by double stranded RNA. RNA...
The discovery of RNA interference (RNAi) gave rise to the development of new nucleic acid-based tech...