Periodontal condition on patients with type 2 diabetes mellitus in urban area of Beijing

目的 调查北京城区的某社区2型糖尿病人群的牙周状况,探讨2型糖尿病与牙周炎的关系.方法 2005年5月至8月对北京市石景山区古城等4个社区内一队列人群的体检结果进行筛查,筛选出118例2型糖尿病患者、78例单纯高血压患者和50名无系统性疾病者进行牙周临床检查,记录全口牙的菌斑指数、出血指数、探诊深度、附着丧失和缺失牙数,比较3组间的牙周指标,并以Logistic回归分析糖尿病与牙周炎的相关性.结果 糖尿病组的缺牙数[(10±8)个]、菌斑指数(2.2±0.5)、探诊深度[(3.6±0.8)mm]、附着丧失[(4.9±1.9)mm]及重度牙周炎患病率(76.3%)均高于高血压组和无系统性疾病组(均P＜0.05);未调整其他因素时,糖尿病患者发生中重度牙周炎的风险是无糖尿病者的5.8～38.9倍;调整了年龄、性别、吸烟、菌斑控制等因素后,糖尿病患者血糖控制情况仍与发生中重度牙周炎独立关联,控制好者OR=6.99,控制差者OR=31.21.结论 北京城区2型糖尿病患者的牙周状况较无糖尿病者差,糖尿病患者血糖控制差可能与发生中重度牙周炎的风险增高独立关联.Objective To investigate the periodontal status of the patients with type 2 diabetes mellitus (T2DM) and to characterize the relationship between periodontitis and diabetes. Methods A total of 118 subjects with T2DM, 78 subjects only with hypertension (HBP) and 50 systemic healthy subjects were enrolled from January to May 2009 in Beijing. Periodontal index including plaque index (PLI),probing depth (PD), bleeding index (BI), attachment loss (AL) and the number of missing teeth were recorded. Then Logistic regression model was set to analyze the relationship between periodontitis and diabetes. Results PLI ( 2.2 ± 0. 5 ), PD ( ( 3.6 ± 0. 8 ) mm), AL ( (4. 9 ± 1.9 ) mm), the number of missing teeth ( 10 ± 8 ) and the prevalence of severe periodontitis (76. 3% ) in diabetic patients were significantly higher than those in both HP and systemic healthy subjects. Compared with non-diabetic subjects, diabetic patients had a higher risk of moderate or severe periodontitis, with OR = 5.8 - 38.9. After adjusting age, gender, smoking and PLI, poorer controlled diabetes was still associated with higher risk of moderate or severe periodontitis with OR = 31.21, while in well-controlled group with OR = 6. 99.Conclusions T2DM patients had poorer periodontal status than non-diabetic subjects. Diabetes, especially poor-controlled subjects, may be associated with increased risk of moderate or severe periodontitis."十一五"国家科技支撑计划中文核心期刊要目总览(PKU)04248-2520