Podoplanin expression in oral squamous cell carcinoma and leukoplakia and its correlation with lymph vessels density

doplanin高表达病例22例(81%)、浸润癌中Podoplanin高表达病例25例(78%),而正常口腔黏膜均不表达Podoplanin.在白斑和早期浸润癌病变上皮附近的微淋巴管密度与病变上皮中Podoplanin的表达强度呈正相关(P<0.05),在浸润癌病变上皮中Podoplanin的表达与癌内微淋巴管密度呈正相关(P<0.05).结论 Podoplanin在口腔癌前病变癌变的发生、癌组织的浸润及癌转移中可能起重要作用.ted stage of squamous cell carcinoma was positively correlated with the lymph vessels density (P < 0. 05). Conclusions Podoplanin expression in different proliferative oral epithelia may be related to oral carcinogenesis,invasion and metastasis.PubMed中文核心期刊要目总览(PKU)中国科技核心期刊(ISTIC)中国科学引文数据库(CSCD)08488-4914